Results 1 to 10 of about 47,279 (194)

Cytoskeletons in the Closet—Subversion in Alphaherpesvirus Infections [PDF]

Viruses, 2018
Actin filaments, microtubules and intermediate filaments form the cytoskeleton of vertebrate cells. Involved in maintaining cell integrity and structure, facilitating cargo and vesicle transport, remodelling surface structures and motility, the ...
Mónica Miranda-Saksena, Anthony Cunningham, Russell J Diefenbach   +2 more
exaly   +5 more sources

Nectin4 restricts pseudorabies virus infection by blocking gD-Nectin1 interaction [PDF]

Journal of Virology
The alphaherpesvirus Pseudorabies virus (PRV), which causes Aujeszky’s disease (AD), primarily infects swine but has zoonotic potential and can infect multiple species, including humans.
Yi Wang, Zongyi Bo, Senhong Zhao, Tanveer Ali Fazlani, Fayu Yang, Zhengshan Feng, Tianxing Cao, Zhonghui Zhang, Wenchao Xue, Shuai Chen, Yupan Qiao, Zixiang Zhu, Genhong Cheng, Yiping Wang, Haixue Zheng, Shilei Zhang   +15 more
doaj   +2 more sources

Alphaherpesvirus glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology

Frontiers in Microbiology, 2022
The viral envelope glycoprotein E (gE) is required for cell-to-cell transmission, anterograde and retrograde neurotransmission, and immune evasion of alphaherpesviruses.
Yaru Ning, Yaru Ning, Yaru Ning, Yalin Huang, Yalin Huang, Yalin Huang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Bin Tian, Bin Tian, Xumin Ou, Xumin Ou, Xumin Ou, Juan Huang, Juan Huang, Juan Huang, Sai Mao, Sai Mao, Sai Mao, Di Sun, Di Sun, Di Sun, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Qun Gao, Qun Gao, Qun Gao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Dekang Zhu, Dekang Zhu, Renyong Jia, Renyong Jia, Renyong Jia   +51 more
exaly   +3 more sources

Molecular Characterization of Highly Pathogenic Marek's Disease Virus Strain in Vaccinated Iraqi Pullets. [PDF]

Adv Virol
Background Marek’s disease (MD) remains a severe economic concern in poultry industry globally despite decades of vaccination strategies. Particularly challenging are viral infections due to Marek’s disease virus (MDV) (Gallid alphaherpesvirus 2, GaHV‐2) strains that can escape immune defenses in areas that do not have access to molecular surveillance ...
Manswr BM, Hamad MA, Ali AEH, Jameel FR.
europepmc   +2 more sources

Alphaherpesvirus gB Homologs Are Targeted to Extracellular Vesicles, but They Differentially Affect MHC Class II Molecules

Viruses, 2020
Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and structure conservation between gB homologs, we asked whether bovine herpesvirus-1 (BoHV-1) and ...
Małgorzata Graul, Andrea Lipinska, Michał Rychłowski   +2 more
exaly   +3 more sources

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era. [PDF]

Eur J Immunol
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Lindahl H, Shaw-Saliba K, Larman HB, Smith CIE, Bergman P.   +4 more
europepmc   +2 more sources

Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]

Microbiologyopen
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Nath BK, Swarbrick CMD, Blades R, Ariawan D, Tietz O, Alvisi G, Forwood JK, Sarker S.   +7 more
europepmc   +2 more sources

The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle

Frontiers in Microbiology
Alphaherpesvirus is a widespread pathogen that causes diverse diseases in humans and animals and can severely damage host health. Alphaherpesvirus particles comprise a DNA core, capsid, tegument and envelope; the tegument is located between the nuclear ...
Yuxi Cui, Yuxi Cui, Yuxi Cui, Yuxi Cui, Yuxi Cui, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Wei Zhang, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Di Sun, Di Sun, Di Sun, Di Sun, Di Sun, Yu He, Yu He, Yu He, Yu He, Yu He, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu   +84 more
exaly   +3 more sources

Pan‐gammaherpesvirus control via a broadly neutralising gB antibody [PDF]

Clin Transl Med
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Jiang Z, Li P, Xie C, Sun C.
europepmc   +2 more sources

Veterinary Herpesviruses: Experimental Tools for Transcriptomics and Neuroscience [PDF]

Veterinary Sciences
Here we discuss three veterinary alphaherpesviruses—pseudorabies virus, equid alphaherpesvirus 1, and bovine alphaherpesvirus 1—that were instrumental in uncovering the true extent of transcriptome complexity through long-read RNA sequencing, which ...
Zsolt Boldogkői, Gábor Torma, Dóra Tombácz   +2 more
doaj   +2 more sources