Results 1 to 10 of about 7,920 (155)

Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome

mBio, 2018
Misincorporation of uracil or spontaneous cytidine deamination is a common mutagenic insult to DNA. Herpesviruses encode a viral uracil-DNA glycosylase (vUNG) and a viral dUTPase (vDUT), each with enzymatic and nonenzymatic functions.
Qiwen Dong, Kyle R. Smith, Darby G. Oldenburg, Maxwell Shapiro, William R. Schutt, Laraib Malik, Joshua B. Plummer, Yunxiang Mu, Thomas MacCarthy, Douglas W. White, Kevin M. McBride, Laurie T. Krug   +11 more
doaj   +1 more source

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source

Model Systems of Gammaherpesvirus Infection, Immunity, and Disease

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT Epstein‐Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) are oncogenic human gammaherpesviruses (GHVs) associated with a broad spectrum of malignancies and chronic diseases. However, direct studies of these viruses in humans are limited by ethical constraints, technical challenges, and their strict species specificity.
Arundhati Gupta, Renfeng Li, Kathy Shair, Shou‐Jiang Gao   +3 more
wiley   +1 more source

ORF6 and ORF61 Expressing MVA Vaccines Impair Early but Not Late Latency in Murine Gammaherpesvirus MHV-68 Infection

Frontiers in Immunology, 2019
Gammaherpesviruses (γHV) are important pathogens causing persistent infections which lead to several malignancies in immunocompromised patients. Murine γHV 68 (MHV-68), a homolog to human EBV and KSHV, has been employed as a classical pathogen to ...
Baila Samreen, Baila Samreen, Sha Tao, Karsten Tischer, Heiko Adler, Ingo Drexler   +5 more
doaj   +1 more source

An outbreak of malignant catarrhal fever in Murrah buffaloes in Minas Gerais, Brazil Surto de febre catarral maligna (FCM) em búfalos da raça Murrah no estado de Minas Gerais

Pesquisa Veterinária Brasileira, 2009
An outbreak of Malignant Catarrhal Fever (MCF) resulted in death of five female buffaloes and one domestic cow from the same farm. Four buffaloes died 10-15 days after the appearance of clinical signs, while the fifth was euthanized in extremis, after ...
Érica A. Costa, Eduardo Bastianetto, Anilton C. Vasconcelos, Maria Rosa Q. Bomfim, Flávio G. da Fonseca, Adriana D. Gomes, Romário C. Leite, Mauricio Resende   +7 more
doaj   +1 more source

Molecular and phylogenetic analysis of herpesviruses in endangered free-ranging cervids of Chile: ovine gammaherpesvirus-2—A novel threat to wild and domestic animal health in Chilean Patagonia

Frontiers in Veterinary Science
IntroductionHerpesvirus infections have been highlighted as emerging diseases affecting wildlife health and the conservation of several taxa. Malignant catarrhal fever (MCF) and infectious keratoconjunctivitis (IKC) are two viruses that infect wild ...
Ezequiel Hidalgo-Hermoso, Javier Cabello, Rodrigo Lopez, Vicente Vergara-Wilson, Frank Vera, Carola Valencia, Carlos Sanchez, Sebastian Celis, Alejandra Silva, Aintzane Cariñanos, Ismael Barria, Rocio Vicencio, Sebastián Muñoz-Leal, Paula Aravena, Rocio Lagos, Juan Toro-Letelier, Sebastián Verasay-Caviedes, Sebastián Verasay-Caviedes, Antonio Garnham, Irene Peña, Irene Peña, Fernando Sánchez, Dario Moreira-Arce, Dario Moreira-Arce, Pablo M. Vergara, Raul Alegria-Moran, Galaxia Cortés-Hinojosa   +26 more
doaj   +1 more source

Long-read transcriptomics of caviid gammaherpesvirus 1: compiling a comprehensive RNA atlas

mSystems
Caviid gammaherpesvirus 1 (CaGHV-1), formerly known as the guinea pig herpes-like virus, is an oncogenic gammaherpesvirus with a sequenced genome but an as-yet uncharacterized transcriptome. Using nanopore long-read RNA sequencing, we annotated the CaGHV-
Gábor Torma, Ákos Dörmő, Ádám Fülöp, Dóra Tombácz, Máté Mizik, Amanda M. Pretory, See-Chi Lee, Zsolt Toth, Zsolt Boldogkői   +8 more
doaj   +1 more source

Ovine Herpesvirus 2 Glycoprotein B Complementation Restores Infectivity to a Bovine Herpesvirus 4 gB-Null Mutant

Pathogens
Ovine herpesvirus 2 (OvHV-2) and bovine herpesvirus 4 (BoHV-4) are gamma herpesviruses that belong to the genera Macavirus and Rhadinovirus, respectively.
Daniela D. Moré, Katherine N. Baker, Smriti Shringi, Reginaldo G. Bastos, Donal O’Toole, Gaetano Donofrio, Cristina W. Cunha   +6 more
doaj   +1 more source

Bovine Gammaherpesvirus 6 Tropism in the Natural Host

Viruses
Bovine gammaherpesvirus 6 (BoHV-6) is endemic in cattle in Europe, with a high prevalence. There is evidence that the virus is a commensal and not associated with disease processes.
Rosalie Fabian, Giuliana Rosato, James P. Stewart, Anja Kipar   +3 more
doaj   +1 more source

Early-life gammaherpesvirus infection results in an expanded long-term latent reservoir. [PDF]

Front Cell Infect Microbiol
Manzi MS, Phophi L, de Oca JMF, Wilt HM, Ensberg KJ, Feswick A, Karst SM, Tibbetts SA.   +7 more
europepmc   +1 more source