Results 31 to 40 of about 7,401 (195)

The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection

Frontiers in Cellular and Infection Microbiology, 2023
Immediately after entry into host cells, viruses are sensed by the innate immune system, leading to the activation of innate antiviral effector mechanisms including the type I interferon (IFN) response and natural killer (NK) cells.
Viktoria Rex, Razieh Zargari, Markus Stempel, Markus Stempel, Stephan Halle, Stephan Halle, Melanie M. Brinkmann, Melanie M. Brinkmann   +7 more
doaj   +1 more source

Gammaherpesvirus Sequence Comparisons [PDF]

Journal of Virology, 1998
In the December 1997 issue, a report by Desrosiers et al. (2) described a novel herpesvirus in rhesus macaques (named RRV for rhesus rhadinovirus) with similarity to human herpesvirus 8 (HHV-8 or KSHV for Kaposi’s sarcoma-associated herpesvirus).
Marnix L. Bosch, Kurt B. Strand, Timothy M. Rose   +2 more
openaire   +1 more source

E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation

Viruses, 2023
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald, Mathew Constantine, Adedolapo Adegbuyi, Esosa Omorogbe, Anna J. Dellomo, Elana S. Ehrlich   +5 more
doaj   +1 more source

Gammaherpesvirus Infection of Human Neuronal Cells [PDF]

mBio, 2015
ABSTRACT Gammaherpesviruses human herpesvirus 4 (HHV4) and HHV8 are two prominent members of the herpesvirus family associated with a number of human cancers. HHV4, also known as Epstein-Barr virus (EBV), a ubiquitous gammaherpesvirus prevalent in 90 to 95% of the human population, is clinically associated with various ...
Hem Chandra Jha, Devan Mehta, Jie Lu, Darine El-Naccache, Sanket K. Shukla, Colleen Kovacsics, Dennis Kolson, Erle S. Robertson   +7 more
openaire   +3 more sources

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. [PDF]

, 2009
Control of gammaherpesvirus infections requires a complex, well orchestrated immune response regulated by positive and negative co-signaling molecules.
Kammerer Robert, Zimmermann, Wolfgang, Adler, Heiko, Guggemoos Simone, El-Gogo, Susanne, El-Gogo, S., Nicole Beauchemin, Beauchemin, Nicole, Heiko Adler, Beauchemin, N., Robert Kammerer, Kammerer, Robert, Kammerer, R., Beauchemin Nicole, Wolfgang Zimmermann, Susanne El-Gogo, Guggemoos, S., Guggemoos, Simone, Adler Heiko, Zimmermann Wolfgang, Zimmermann, W., Adler, H., El-Gogo Susanne, Simone Guggemoos   +23 more
core   +1 more source

A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018

Frontiers in Veterinary Science, 2021
Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland, Morten Tryland, Javier Sánchez Romano, Ingebjørg Helena Nymo, Eva Marie Breines, Francisco Javier Ancin Murguzur, Ole Christian Kjenstad, Hong Li, Hong Li, Cristina W. Cunha, Cristina W. Cunha   +10 more
doaj   +1 more source

T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells

mBio, 2022
Gammaherpesviruses establish lifelong infections in most vertebrate species, including humans and rodents, and are associated with cancers, including B cell lymphomas.
P. A. Sylvester, C. N. Jondle, D. L. Schmalzriedt, B. N. Dittel, V. L. Tarakanova   +4 more
doaj   +1 more source

Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]

, 2012
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B., Knowles, Sarah L.K., Fenton, Andy   +2 more
core   +1 more source

A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB. [PDF]

, 2010
Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 ...
Stewart, James P., Stipan, J., Adler, Heiko, James P Stewart, Adler Barbara, Adler, Barbara, Heiko Adler, Beatrix Steer, Barbara Adler, Jonjic Stipan, Stipan Jonjic, Steer, Beatrix, Steer Beatrix, Steer, B., Adler Heiko, Stewart James P., Adler, H., Adler, B., Jonjic, Stipan, James P. Stewart, Stewart, J.P.   +20 more
core   +1 more source

A gammaherpesviral internal repeat contributes to latency amplification. [PDF]

, 2007
Gammaherpesviruses cause important infections of humans, in particular in immunocompromised patients. The genomes of gammaherpesviruses contain variable numbers of internal repeats whose precise role for in vivo pathogenesis is not well understood.
Steer, Beatrix, Susanne El-Gogo, Andreas Waha, Adler, Heiko, El-Gogo, Susanne, Thakur, Nagendra N., Freimüller, Klaus, Waha, Andreas, Heiko Adler, Nagendra N Thakur, Beatrix Steer, Klaus Freimüller   +11 more
core   +1 more source