Results 31 to 40 of about 7,920 (155)

E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation

Viruses, 2023
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald, Mathew Constantine, Adedolapo Adegbuyi, Esosa Omorogbe, Anna J. Dellomo, Elana S. Ehrlich   +5 more
doaj   +1 more source

A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018

Frontiers in Veterinary Science, 2021
Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland, Morten Tryland, Javier Sánchez Romano, Ingebjørg Helena Nymo, Eva Marie Breines, Francisco Javier Ancin Murguzur, Ole Christian Kjenstad, Hong Li, Hong Li, Cristina W. Cunha, Cristina W. Cunha   +10 more
doaj   +1 more source

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. [PDF]

, 2009
Control of gammaherpesvirus infections requires a complex, well orchestrated immune response regulated by positive and negative co-signaling molecules.
Kammerer Robert, Zimmermann, Wolfgang, Adler, Heiko, Guggemoos Simone, El-Gogo, Susanne, El-Gogo, S., Nicole Beauchemin, Beauchemin, Nicole, Heiko Adler, Beauchemin, N., Robert Kammerer, Kammerer, Robert, Kammerer, R., Beauchemin Nicole, Wolfgang Zimmermann, Susanne El-Gogo, Guggemoos, S., Guggemoos, Simone, Adler Heiko, Zimmermann Wolfgang, Zimmermann, W., Adler, H., El-Gogo Susanne, Simone Guggemoos   +23 more
core   +2 more sources

T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells

mBio, 2022
Gammaherpesviruses establish lifelong infections in most vertebrate species, including humans and rodents, and are associated with cancers, including B cell lymphomas.
P. A. Sylvester, C. N. Jondle, D. L. Schmalzriedt, B. N. Dittel, V. L. Tarakanova   +4 more
doaj   +1 more source

Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]

, 2012
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B., Knowles, Sarah L.K., Fenton, Andy   +2 more
core   +1 more source

A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB. [PDF]

, 2010
Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 ...
Stewart, James P., Stipan, J., Adler, Heiko, James P Stewart, Adler Barbara, Adler, Barbara, Heiko Adler, Beatrix Steer, Barbara Adler, Jonjic Stipan, Stipan Jonjic, Steer, Beatrix, Steer Beatrix, Steer, B., Adler Heiko, Stewart James P., Adler, H., Adler, B., Jonjic, Stipan, James P. Stewart, Stewart, J.P.   +20 more
core   +1 more source

Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract [PDF]

, 2014
This work was supported by a Royal Society (London) University Research Fellowship (to JPS), by Biotechnology and Biological Sciences Research Council (UK) grants BB/K009664/1 (to JPS, AK, and GHL) and BB/K009737/1 (CDB and LB), US Public Health Service ...
Leeming, G H, Moyo, NA, Bingle, Colin D, Bigley, A.L., Tripp, Ralph A, Bennett, E., Hughes, D J, Leeming, G.H., Moyo, N A, Bingle, L, Bigley, AL, Sample, JT, Bigley, Alison L, Bigley, A L, Tripp, R A, Sample, J T, Kipar, A, Moyo, Nathifa A, Stewart, JP, Stewart, J.P., Bennett, E, Tripp, R.A., Hughes, DJ, Kipar, A., Tripp, RA, Stewart, James P, Bingle, Lynne, Bennett, Elaine, Hughes, D.J., Leeming, Gail H, Sample, Jeffery T, Bingle, C D, Leeming, GH, Moyo, N.A., Sample, J.T., Moyo, Nathifa, Hughes, David J, Kipar, Anja, Bingle, CD, Bingle, L., Bingle, C.D., Stewart, J P   +41 more
core   +1 more source

A Gammaherpesvirus MicroRNA Targets EWSR1 (Ewing Sarcoma Breakpoint Region 1) In Vivo To Promote Latent Infection of Germinal Center B Cells

mBio, 2019
Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), directly contribute to the genesis of multiple types of malignancies, including B cell lymphomas. In vivo, these viruses infect
Yiping Wang, Emily R. Feldman, Whitney L. Bullard, Scott A. Tibbetts   +3 more
doaj   +1 more source

Effects of Mustelid gammaherpesvirus 1 (MusGHV-1) Reactivation in European Badger (Meles meles) Genital Tracts on Reproductive Fitness

Pathogens, 2020
Reactivation of latent Gammaherpesvirus in the genital tract can lead to reproductive failure in domestic animals. Nevertheless, this pathophysiology has not received formal study in wild mammals. High prevalence of Mustelid gammaherpesvirus 1 (MusGHV-1)
Ming-shan Tsai, Ursula Fogarty, Andrew W. Byrne, James O’Keeffe, Chris Newman, David W. Macdonald, Christina D. Buesching   +6 more
doaj   +1 more source

A gammaherpesviral internal repeat contributes to latency amplification. [PDF]

, 2007
Gammaherpesviruses cause important infections of humans, in particular in immunocompromised patients. The genomes of gammaherpesviruses contain variable numbers of internal repeats whose precise role for in vivo pathogenesis is not well understood.
Steer, Beatrix, Susanne El-Gogo, Andreas Waha, Adler, Heiko, El-Gogo, Susanne, Thakur, Nagendra N., Freimüller, Klaus, Waha, Andreas, Heiko Adler, Nagendra N Thakur, Beatrix Steer, Klaus Freimüller   +11 more
core   +2 more sources