Results 51 to 60 of about 7,401 (195)

Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues

mSphere, 2023
Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair.
Kyle R. Smith, Somnath Paul, Qiwen Dong, Orchi Anannya, Darby G. Oldenburg, J. Craig Forrest, Kevin M. McBride, Laurie T. Krug   +7 more
doaj   +1 more source

RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency

Pathogens, 2017
RTA, the viral Replication and Transcription Activator, is essential for rhadinovirus lytic gene expression upon de novo infection and reactivation from latency.
Alexis L. Santana, Darby G. Oldenburg, Varvara Kirillov, Laraib Malik, Qiwen Dong, Roman Sinayev, Kenneth B. Marcu, Douglas W. White, Laurie T. Krug   +8 more
doaj   +1 more source

Gammaherpesvirus in Cervid Species from Norway: Characterization of a New Virus in Wild and Semi-Domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus)

Viruses, 2020
Gammaherpesvirus infections have been described in cervids worldwide, mainly the genera Macavirus or Rhadinovirus. However, little is known about the gammaherpesviruses species infecting cervids in Norway and Fennoscandia.
Carlos G. das Neves, Carlos Sacristán, Knut Madslien, Morten Tryland   +3 more
doaj   +1 more source

Inhibition of Host Gene Expression by KSHV: Sabotaging mRNA Stability and Nuclear Export

Frontiers in Cellular and Infection Microbiology, 2021
Viruses are known for their ability to alter host gene expression. Kaposi sarcoma-associated herpesvirus has two proteins that obstruct host gene expression.
Carissa Ikka Pardamean, Ting-Ting Wu
doaj   +1 more source

Tick-Borne Transmission of Murine Gammaherpesvirus 68 [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Herpesviruses are a large group of DNA viruses infecting mainly vertebrates. Murine gammaherpesvirus 68 (MHV68) is often used as a model in studies of the pathogenesis of clinically important human gammaherpesviruses such as Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus.
Valeria Hajnická, Marcela Kúdelová, Iveta Štibrániová, Mirko Slovák, Pavlína Bartíková, Zuzana Halásová, Peter Pančík, Petra Belvončíková, Michaela Vrbová, Viera Holíková, Rosemary S. Hails, Patricia A. Nuttall, Patricia A. Nuttall   +12 more
openaire   +6 more sources

Prevalence, Geographic Distribution, Risk Factors and Co-Infections of Feline Gammaherpesvirus Infections in Domestic Cats in Switzerland

Viruses, 2019
Recently, a gammaherpesvirus was described in domestic cats (FcaGHV1). The goal of the present study was to investigate the presence of FcaGHV1 in Swiss domestic cats and analyze potential risk factors.
Marilisa Novacco, Neda Ranjbar Kohan, Martina Stirn, Marina L. Meli, Adrian Alberto Díaz-Sánchez, Felicitas S. Boretti, Regina Hofmann-Lehmann   +6 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Long Non-coding RNAs in Gammaherpesvirus Infections: Their Roles in Tumorigenic Mechanisms

Frontiers in Microbiology, 2021
Long non-coding RNAs (lncRNAs) regulate gene expression at the epigenetic, transcriptional, or posttranscriptional level by interacting with protein, DNA, and RNA.
Wen Liu, Yan Zhang, Yan Zhang, Bing Luo
doaj   +1 more source

Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus‐Associated Disorders

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype. Case This case describes an antiretroviral therapy‐adherent person with HIV who presented with concurrent KSHV‐related disorders of Kaposi ...
Kandice Roberts, Paula Valiño Ramos, Saurabh Jindal, Vikas Prasad, Yi Shan Lee, Mariam Khanfar, Obi L. Griffith, Malachi Griffith, Jeanne Jiang, Ethel Cesarman, Daniel Rauch, Paul Simonson, Thomas Odeny, Lee Ratner   +13 more
wiley   +1 more source

KSHV Genome in Saliva, Whole Blood and Kaposi's Sarcoma Biopsy Specimens in Republic of Congo: Phylogenetic Analysis and an APOBEC3B Mutational Signature

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) has been associated with a variety of diseases and is endemic in Sub‐Saharan Africa. We performed KSHV‐whole‐genome analysis and search for APOBEC‐editing to describe genetic diversity in samples issued from an endemic region.
Gervillien Arnold Malonga, Valentin Leducq, Antoine Fauchois, Dimitry Moudiongui Mboungou Malanda, Patrina Joseph Iloukou Mayakia, Juthèce Private Malanda‐Kiminou, Ferdinand Emaniel Brel Got, Fabien Gaël Mouamba, Vincent Calvez, Jean Felix Peko, Anne‑Geneviève Marcelin, Aude Jary   +11 more
wiley   +1 more source