Results 71 to 80 of about 7,401 (195)
Vaccines, 2021 An efficacious vaccine for sheep-associated malignant catarrhal fever (SA-MCF) is important for the livestock industry. Research towards SA-MCF vaccine development is hindered by the absence of culture systems to propagate the causative agent, ovine ...
Smriti Shringi +7 more
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Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients [PDF]
Cancer Letters, 2011 Two lymphotropic human gamma herpesviruses can cause lymphoproliferative disorders: Epstein Barr virus (EBV, formally designated as human herpesvirus 4) and Kaposi sarcoma herpesvirus (KSHV, also called human herpesvirus 8). Individuals with inherited or acquired immunodeficiency have a greatly increased risk of developing a malignancy caused by one of
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Virus-Encoded MicroRNAs Facilitate Gammaherpesvirus Latency and Pathogenesis
mBio, 2014 Gammaherpesviruses, including Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV, or HHV-8), and murine gammaherpesvirus 68 (MHV68, γHV68, or MuHV-4), are B cell-tropic pathogens that each encode at least 12 microRNAs (miRNAs).
Emily R. Feldman +8 more
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Viruses, 2022 Human respiratory syncytial virus (hRSV) infection brings a wide spectrum of clinical outcomes, from a mild cold to severe bronchiolitis or even acute interstitial pneumonia. Among the known factors influencing this clinical diversity, genetic background
Gautier Gilliaux, Daniel Desmecht
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Latent, Lytic, and Linked to Multiple Sclerosis—How EBV Drives Autoimmunity
European Journal of Immunology, Volume 56, Issue 2, February 2026.EBV latent and lytic genes uniquely contribute to Multiple Sclerosis development by various immunopathogenic mechanisms in susceptible hosts. Briefly, EBV infection shapes the B‐cell repertoire and promotes the oligoclonal expansion and subsequent CNS infiltration of T‐bet+CXCR3+ B cells, resulting in a cascade of immune dysregulation, CNS inflammation,
Fabienne Läderach +2 more
wiley +1 more source
Pathogens, 2020 Epstein−Barr virus (EBV) is involved in the pathogenesis of various lymphomas and carcinomas, whereas Kaposi’s sarcoma-associated herpesvirus (KSHV) participates in the pathogenesis of endothelial sarcoma and lymphomas.
Shigeyoshi Fujiwara, Hiroyuki Nakamura
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Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.Pulmonary infections remain a significant global health burden, particularly in immunocompromised individuals and patients with chronic respiratory or systemic diseases. Conventional microbiological tests (CMTs), though widely used, often have limited sensitivity and delayed results, especially in polymicrobial or atypical infections.
Ying Zhao +7 more
wiley +1 more source
Acta virologica, 2001 In 1976, within a project on isolation of herpesviruses from small rodents in former Czechoslovakia, the mouse herpesvirus strain 68 (MHV-68) was isolated (Blaskovic et al., 1980). This virus was accepted by The International Committee on Taxonomy of Viruses (ICTV) as a new, so far unassigned species (member) of the Gammaherpesvirinae subfamily of the ...
J, Mistríková +3 more
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Antibody Evasion by a Gammaherpesvirus O-Glycan Shield
PLoS Pathogens, 2011 All gammaherpesviruses encode a major glycoprotein homologous to the Epstein-Barr virus gp350. These glycoproteins are often involved in cell binding, and some provide neutralization targets. However, the capacity of gammaherpesviruses for long-term transmission from immune hosts implies that in vivo neutralization is incomplete. In this study, we used
Machiels, Bénédicte +6 more
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VirusesGammaherpesviruses are oncogenic pathogens that establish lifelong infections. There are no FDA-approved vaccines against Epstein–Barr virus or Kaposi sarcoma herpesvirus.
Dipanwita Mitra +3 more
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