Results 71 to 80 of about 7,920 (155)

Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues

mSphere, 2023
Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair.
Kyle R. Smith, Somnath Paul, Qiwen Dong, Orchi Anannya, Darby G. Oldenburg, J. Craig Forrest, Kevin M. McBride, Laurie T. Krug   +7 more
doaj   +1 more source

An Optimized Protocol for the Generation of iPSC Lines from Lymphoblastoid Cell Lines Using the Non‐integrative Sendai Virus

Current Protocols, Volume 6, Issue 3, March 2026.
Abstract The choice of cell source for generating induced pluripotent stem cells (iPSCs) is influenced by several factors, including accessibility, reprogramming efficiency, and the invasiveness of the cell collection procedure. Traditional sources such as skin fibroblasts or peripheral blood mononuclear cells often require invasive sampling, which can
Laurie Martineau, Isabella Bienjonetti, Sabrina Bellenfant, Jack Puymirat, François Gros‐Louis   +4 more
wiley   +1 more source

The m4 gene of murine gammaherpesvirus modulates productive and latent infection in vivo [PDF]

, 2003
Murine gammaherpesvirus 68 (MHV-68) infection of mice represents a viable small-animal model for the study of gammaherpesvirus pathogenesis. MHV-76 is a deletion mutant of MHV-68, which lacks four MHV-68-specific genes (M1 to M4) and eight viral tRNA ...
Dutia, B M, Townsley, A C, Gene Murine Gammaherpesvirus, Nash, A A, The M   +4 more
core  

Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity. [PDF]

, 2015
Immunity to non-cerebral severe malaria is estimated to occur within 1-2 infections in areas of endemic transmission for Plasmodium falciparum. Yet, nearly 20% of infected children die annually as a result of severe malaria.
Brigid M O'Flaherty, Caline G. Matar (742589), Samuel H Speck, Nathan T Jacobs, Neil R. Anthony (528857), Samuel H. Speck (70359), Tracey J Lamb, Lalita Priyamvada (421536), Anthony, Neil R, Christian R. Engwerda (42442), Priyamvada, Lalita, Caline G Matar, Jacobs, Nathan T, Lalita Priyamvada, Lamb, Tracey J, Matar, Caline G, O'Flaherty, Brigid M, Tracey J. Lamb (659393), Engwerda, Christian R, Christian R Engwerda, Speck, Samuel H, Brigid M. O’Flaherty (615607), Nathan T. Jacobs (742590), Neil R Anthony   +23 more
core   +1 more source

Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection

Viruses
Gammaherpesviruses are oncogenic pathogens that establish lifelong infections. There are no FDA-approved vaccines against Epstein–Barr virus or Kaposi sarcoma herpesvirus.
Dipanwita Mitra, Darby G. Oldenburg, J. Craig Forrest, Laurie T. Krug   +3 more
doaj   +1 more source

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

Endothelial cells support persistent gammaherpesvirus 68 infection. [PDF]

, 2008
A variety of human diseases are associated with gammaherpesviruses, including neoplasms of lymphocytes (e.g. Burkitt's lymphoma) and endothelial cells (e.g. Kaposi's sarcoma).
Andrea Luísa Suárez, Linda Faye van Dyk, van Dyk Linda Faye, Suárez Andrea Luísa   +3 more
core   +1 more source

Virus‐Dependent Geographic Structure of Co‐Circulating Viruses in a Single Bat Species

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Understanding the spatial spread of viruses within wildlife populations is often a key component of disease management efforts. Viral spread is likely constrained by host ecology, but inter‐virus differences in infection strategy might allow some viruses to overcome these constraints, leading to divergent population structures within a common ...
Avery L. Holmes, Alice Broos, Daniel J. Becker, Jorge E. Carrera, Maxwell J. Farrell, Rita Ribeiro, Carlos Tello, Laura M. Bergner, Daniel G. Streicker   +8 more
wiley   +1 more source

Latent, Lytic, and Linked to Multiple Sclerosis—How EBV Drives Autoimmunity

European Journal of Immunology, Volume 56, Issue 2, February 2026.
EBV latent and lytic genes uniquely contribute to Multiple Sclerosis development by various immunopathogenic mechanisms in susceptible hosts. Briefly, EBV infection shapes the B‐cell repertoire and promotes the oligoclonal expansion and subsequent CNS infiltration of T‐bet+CXCR3+ B cells, resulting in a cascade of immune dysregulation, CNS inflammation,
Fabienne Läderach, Elena Bremer, Christian Münz   +2 more
wiley   +1 more source

TLR9 contributes to antiviral immunity during gammaherpesvirus infection.

, 2008
The human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and EBV cause important infections. As pathogenetic studies of the human infections are restricted, murine gammaherpesvirus 68 serves as a model to study gammaherpesvirus ...
Guggemoos, S., Heit, A., Bauer, S., Adler, H., Hamm, S., Hangel, D.   +5 more
core   +2 more sources