Results 91 to 100 of about 7,401 (195)
Prognostic factors in bushfire‐affected koalas–Kangaroo Island bushfire response 2020
Australian Veterinary Journal, Volume 103, Issue 8, Page 453-463, August 2025.This study presents a retrospective analysis of clinical records data from koalas presenting for treatment following the large‐scale bushfire event on Kangaroo Island 2019–2020. The aim of the study was to identify prognostic factors for koalas affected by bushfire. Koalas (n = 199) were grouped based on their burn status in combination with their burn
O Funnell +6 more
wiley +1 more source
Glycosaminoglycan Interactions in Murine Gammaherpesvirus-68 Infection
PLoS ONE, 2007 Glycosaminoglycans (GAGs) commonly participate in herpesvirus entry. They are thought to provide a reversible attachment to cells that promotes subsequent receptor binding. Murine gamma-herpesvirus-68 (MHV-68) infection of fibroblasts and epithelial cells is highly GAG-dependent.
Gillet, Laurent +2 more
openaire +6 more sources
Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity.
, 2015 Immunity to non-cerebral severe malaria is estimated to occur within 1-2 infections in areas of endemic transmission for Plasmodium falciparum. Yet, nearly 20% of infected children die annually as a result of severe malaria.
Brigid M O'Flaherty +23 more
core +1 more source
Viruses, 2018 The pathogenicity of Felis catus gammaherpesvirus 1 (FcaGHV1), a common infection of domestic cats, is unknown. To explore an association between FcaGHV1 detection and feline lymphoma, a retrospective, cross-sectional, disease-association study was ...
Alicia J. McLuckie +5 more
doaj +1 more source
KSHV vIL6 Inhibits Functional B Cell Maturation During De Novo Infection
Journal of Medical Virology, Volume 97, Issue 7, July 2025.ABSTRACT Despite causative links to lymphoproliferative disorders, little is known about early events governing KSHV infection in B lymphocytes. IL‐6 signaling plays a critical role in KSHV‐mediated disease, with human IL‐6 (hIL6) levels correlating with viral load and disease progression.
Wajd Zakir +2 more
wiley +1 more source
, 1994 Murine gammaherpesvirus 68 (MHV-68) is a natural pathogen of murid rodents and displays similar pathobiological characteristics to those of the human gammaherpesvirus Epstein-Barr virus (EBV).
Sunil-Chandra, N P +4 more
core
Age-associated B cells in gammaherpesvirus infection and autoimmunity
, 2022 Multiple sclerosis (MS) and rheumatoid arthritis (RA) are two of the most common autoimmune diseases, but the etiologies are not well understood. Both genetic and environmental factors contribute to disease susceptibility.
Mouat, Isobel C.
core
PARP1 Inhibition Halts EBV+ Lymphoma Progression by Disrupting the EBNA2/MYC Axis
Journal of Medical Virology, Volume 97, Issue 7, July 2025.ABSTRACT PARP1 has been shown to regulate EBV latency. However, the therapeutic effect of PARP1 inhibitors on EBV+ lymphomagenesis has not yet been explored. Here, we show that PARPi BMN 673 has a potent antitumor effect on EBV‐driven LCL in a mouse xenograft model. We found that PARP1 inhibition induces a dramatic transcriptional reprogramming of LCLs
Lisa Beatrice Caruso +10 more
wiley +1 more source
Endothelial cells support persistent gammaherpesvirus 68 infection.
, 2008 A variety of human diseases are associated with gammaherpesviruses, including neoplasms of lymphocytes (e.g. Burkitt's lymphoma) and endothelial cells (e.g. Kaposi's sarcoma).
Andrea Luísa Suárez +3 more
core +1 more source
Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells
, 2021 Epstein-Barr virus (EBV) infection is associated with rheumatoid arthritis (RA) in adults, though the nature of the relationship remains unknown. Herein, we have examined the contribution of viral infection to the severity of arthritis in mice.
Isobel C Mouat +4 more
core +1 more source