Results 101 to 110 of about 7,401 (195)

Epidemiology and pathological progression of erythematous lip lesions in captive sun bears (Helarctos malayanus).

open access: yesPLoS ONE, 2020
This study investigates the occurrence of erythematous lip lesions in a captive sun bear population in Cambodia, including the progression of cheilitis to squamous cell carcinoma, and the presence of Ursid gammaherpesvirus 1.
Kirsty Officer   +9 more
doaj   +1 more source

B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection

open access: yes, 2017
Manipulation of host cellular pathways is a strategy employed by gammaherpesviruses, including mouse gammaherpesvirus 68 (MHV68), in order to negotiate a chronic infection.
Eric J. Darrah   +7 more
core   +1 more source

First description of a Gammaherpesvirus in a common dolphin (Delphinus delphis) from the Eastern Mediterranean Sea

open access: yes, 2023
In September 2020, a male common dolphin (Delphinus delphis) was found dead on a beach near Bat-Yam, Israel. A small, raised, well circumscribed penile lesion (i.e., mass) was identified and removed for histology and molecular characterizations.
Segura Göthlin, Simona Andrea   +10 more
core   +1 more source

Packaging of viral microRNAs in gammaherpesvirus 68

open access: yes, 2013
MicroRNAs are a characteristic of many herpesvirus genomes. These short, non-coding RNAs are capable of post-transcriptional regulation of target mRNAs. Recently, packaged miRNAs have been observed in purified virions of EBV and KSHV, gammaherpesviruses ...
Lutz, Jessica
core   +1 more source

Liver X Receptors Suppress Activity of Cholesterol and Fatty Acid Synthesis Pathways To Oppose Gammaherpesvirus Replication

open access: yesmBio, 2018
Gammaherpesviruses are oncogenic pathogens that persist in ~95% of the adult population. Cellular metabolic pathways have emerged as important regulators of many viral infections, including infections by gammaherpesviruses that require several lipid ...
P. T. Lange   +3 more
doaj   +1 more source

Keeping it quiet: chromatin control of gammaherpesvirus latency [PDF]

open access: yesNature Reviews Microbiology, 2013
The human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) establish long-term latent infections associated with diverse human cancers. Viral oncogenesis depends on the ability of the latent viral genome to persist in host nuclei as episomes that express a restricted yet dynamic pattern of viral genes ...
openaire   +2 more sources

Latent Antigen Vaccination in a Model Gammaherpesvirus Infection

open access: yes, 2001
Vaccines that can reduce the load of latent gammaherpesvirus infections are eagerly sought. One attractive strategy is vaccination against latency-associated proteins, which may increase the efficiency with which T cells recognize and eliminate latently ...
Edward J. Usherwood   +4 more
core   +1 more source

Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1

open access: yes, 2008
The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs.
Stewart, James P.   +5 more
core  

Interpreting the Epstein-Barr Virus (EBV) Epigenome Using High-Throughput Data

open access: yesViruses, 2013
The Epstein-Barr virus (EBV) double-stranded DNA genome is subject to extensive epigenetic regulation. Large consortiums and individual labs have generated a vast number of genome-wide data sets on human lymphoblastoid and other cell lines latently ...
Paul M. Lieberman   +2 more
doaj   +1 more source

The m4 gene of murine gammaherpesvirus modulates productive and latent infection in vivo

open access: yes, 2003
Murine gammaherpesvirus 68 (MHV-68) infection of mice represents a viable small-animal model for the study of gammaherpesvirus pathogenesis. MHV-76 is a deletion mutant of MHV-68, which lacks four MHV-68-specific genes (M1 to M4) and eight viral tRNA ...
Dutia, B M   +4 more
core  

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