Results 61 to 70 of about 7,401 (195)

Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line

mSphere, 2016
While employing deep sequencing and de novo assembly to characterize the mRNA transcript profile of a cell line derived from the microbat Myotis velifer incautus, we serendipitously identified mRNAs encoding proteins with a high level of identity to ...
Reed S. Shabman, Susmita Shrivastava, Tshidi Tsibane, Oliver Attie, Anitha Jayaprakash, Chad E. Mire, Kari E. Dilley, Vinita Puri, Timothy B. Stockwell, Thomas W. Geisbert, Ravi Sachidanandam, Christopher F. Basler   +11 more
doaj   +1 more source

DESIGN AND GENERATION OF A RECOMBINANT GAMMAHERPESVIRUS ENCODING shRNA FROM A NATIVE VIRAL tRNA PROMOTER

Trakya University Journal of Natural Sciences, 2023
Gammaherpesviruses are associated with multiple types of tumor development and understanding the pathogenesis of these viruses has been the subject of various studies.
Scott Tibbetts, Mehmet Kara
doaj   +1 more source

Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski, Mary Alice Allnutt, Kory Johnson, Toshiko Tanaka, Luigi Ferrucci, Huw Morris, John Hardy, PROSPECT Consortium, Mina Ryten, United Kingdom Brain Expression Consortium (UKBEC), Giancarlo Logroscino, Juan Troncoso, Thomas G. Beach, Geidy E. Serrano, Carlos Cruchaga, Dennis W. Dickson, Owen A. Ross, Adriano Chiò, International LBD Genomics Consortium, International ALS Genomics Consortium, Henry Houlden, The American Genome Center, Clifton L. Dalgard, Jinhui Ding, J. Raphael Gibbs, Bryan J. Traynor, Sonja W. Scholz, Steven Jacobson   +27 more
wiley   +1 more source

An Optimized Protocol for the Generation of iPSC Lines from Lymphoblastoid Cell Lines Using the Non‐integrative Sendai Virus

Current Protocols, Volume 6, Issue 3, March 2026.
Abstract The choice of cell source for generating induced pluripotent stem cells (iPSCs) is influenced by several factors, including accessibility, reprogramming efficiency, and the invasiveness of the cell collection procedure. Traditional sources such as skin fibroblasts or peripheral blood mononuclear cells often require invasive sampling, which can
Laurie Martineau, Isabella Bienjonetti, Sabrina Bellenfant, Jack Puymirat, François Gros‐Louis   +4 more
wiley   +1 more source

New insights into the range and transmission dynamics of a koala gammaherpesvirus, phascolarctid gammaherpesvirus 2

Scientific Reports
The recent classification of the koala to endangered across most of its range has emphasised the urgent need for enhanced disease surveillance. Little is known about the distribution and clinical significance of phascolarctid gammaherpesvirus 2 (PhaHV-2) outside the Australian states of Victoria and South Australia. PhaHV-2 may have significant impacts
Chloe Church, Andrea Casteriano, Yasmine SS. Muir, Mark Krockenberger, Paola K. Vaz, Damien P. Higgins, Belinda R. Wright   +6 more
openaire   +3 more sources

Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo

mBio, 2016
A challenging property of gammaherpesviruses is their ability to establish lifelong persistence. The establishment of latency in B cells is thought to involve active virus engagement of host signaling pathways.
Sandeep Steven Reddy, Hui-Chen Chang Foreman, Thubten Ozula Sioux, Gee Ho Park, Valeria Poli, Nancy C. Reich, Laurie T. Krug   +6 more
doaj   +1 more source

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

BAFF Receptor Deficiency Limits Gammaherpesvirus Infection [PDF]

Journal of Virology, 2014
ABSTRACTLymphocyte colonization by gammaherpesviruses (γHVs) is an important target for cancer prevention. However, how it works is not clear. Epstein-Barr virus drives autonomous B cell proliferationin vitrobutin vivomay more subtly exploit the proliferative pathways provided by lymphoid germinal centers (GCs).
Frederico, Bruno, May, Janet S., Efstathiou, Stacey, Stevenson, Philip G.   +3 more
openaire   +5 more sources

Virus‐Dependent Geographic Structure of Co‐Circulating Viruses in a Single Bat Species

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Understanding the spatial spread of viruses within wildlife populations is often a key component of disease management efforts. Viral spread is likely constrained by host ecology, but inter‐virus differences in infection strategy might allow some viruses to overcome these constraints, leading to divergent population structures within a common ...
Avery L. Holmes, Alice Broos, Daniel J. Becker, Jorge E. Carrera, Maxwell J. Farrell, Rita Ribeiro, Carlos Tello, Laura M. Bergner, Daniel G. Streicker   +8 more
wiley   +1 more source

TLR9 contributes to antiviral immunity during gammaherpesvirus infection.

, 2008
The human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and EBV cause important infections. As pathogenetic studies of the human infections are restricted, murine gammaherpesvirus 68 serves as a model to study gammaherpesvirus ...
Guggemoos, S., Heit, A., Bauer, S., Adler, H., Hamm, S., Hangel, D.   +5 more
core   +2 more sources