Results 41 to 50 of about 7,401 (195)

Pathogenesis of a Model Gammaherpesvirus in a Natural Host [PDF]

Journal of Virology, 2010
ABSTRACT Murine gammaherpesvirus 68 (MHV-68) infection of laboratory mice ( Mus musculus ) is an established model of gammaherpesvirus pathogenesis. The fact that M. musculus is not a host in the wild prompted us to reassess MHV-68 infection in wood mice ( Apodemus ...
David J, Hughes, Anja, Kipar, Jeffery T, Sample, James P, Stewart   +3 more
openaire   +2 more sources

Effects of Mustelid gammaherpesvirus 1 (MusGHV-1) Reactivation in European Badger (Meles meles) Genital Tracts on Reproductive Fitness

Pathogens, 2020
Reactivation of latent Gammaherpesvirus in the genital tract can lead to reproductive failure in domestic animals. Nevertheless, this pathophysiology has not received formal study in wild mammals. High prevalence of Mustelid gammaherpesvirus 1 (MusGHV-1)
Ming-shan Tsai, Ursula Fogarty, Andrew W. Byrne, James O’Keeffe, Chris Newman, David W. Macdonald, Christina D. Buesching   +6 more
doaj   +1 more source

Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract [PDF]

, 2014
This work was supported by a Royal Society (London) University Research Fellowship (to JPS), by Biotechnology and Biological Sciences Research Council (UK) grants BB/K009664/1 (to JPS, AK, and GHL) and BB/K009737/1 (CDB and LB), US Public Health Service ...
Leeming, G H, Moyo, NA, Bingle, Colin D, Bigley, A.L., Tripp, Ralph A, Bennett, E., Hughes, D J, Leeming, G.H., Moyo, N A, Bingle, L, Bigley, AL, Sample, JT, Bigley, Alison L, Bigley, A L, Tripp, R A, Sample, J T, Kipar, A, Moyo, Nathifa A, Stewart, JP, Stewart, J.P., Bennett, E, Tripp, R.A., Hughes, DJ, Kipar, A., Tripp, RA, Stewart, James P, Bingle, Lynne, Bennett, Elaine, Hughes, D.J., Leeming, Gail H, Sample, Jeffery T, Bingle, C D, Leeming, GH, Moyo, N.A., Sample, J.T., Moyo, Nathifa, Hughes, David J, Kipar, Anja, Bingle, CD, Bingle, L., Bingle, C.D., Stewart, J P   +41 more
core   +1 more source

Detection of a new bat gammaherpesvirus in the Philippines [PDF]

Virus Genes, 2009
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Watanabe, Shumpei, Ueda, Naoya, Iha, Koichiro, Masangkay, Joseph S., Fujii, Hikaru, Alviola, Phillip, Mizutani, Tetsuya, Maeda, Ken, Yamane, Daisuke, Walid, Azab, Kato, Kentaro, Kyuwa, Shigeru, Tohya, Yukinobu, Yoshikawa, Yasuhiro, Akashi, Hiroomi   +14 more
openaire   +3 more sources

A Gammaherpesvirus MicroRNA Targets EWSR1 (Ewing Sarcoma Breakpoint Region 1) In Vivo To Promote Latent Infection of Germinal Center B Cells

mBio, 2019
Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), directly contribute to the genesis of multiple types of malignancies, including B cell lymphomas. In vivo, these viruses infect
Yiping Wang, Emily R. Feldman, Whitney L. Bullard, Scott A. Tibbetts   +3 more
doaj   +1 more source

Transcription Program of Murine Gammaherpesvirus 68 [PDF]

Journal of Virology, 2003
ABSTRACT Murine gammaherpesvirus 68 (MHV-68 [also referred to as γHV68]) is phylogenetically related to Kaposi's sarcoma-associated herpesvirus (KSHV [also referred to as HHV-8]) and Epstein-Barr virus (EBV). However, unlike KSHV or EBV, MHV-68 readily infects fibroblast and epithelial cell lines derived from several mammalian species ...
DeeAnn, Martinez-Guzman, Tammy, Rickabaugh, Ting-Ting, Wu, Helen, Brown, Steven, Cole, Moon Jung, Song, Leming, Tong, Ren, Sun   +7 more
openaire   +2 more sources

Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire

Viruses, 2020
A common biologic property of the gammaherpesviruses Epstein–Barr Virus and Kaposi sarcoma herpesvirus is their use of B lymphocytes as a reservoir of latency in healthy individuals that can undergo oncogenic transformation later in life ...
Monika A. Zelazowska, Kevin McBride, Laurie T. Krug   +2 more
doaj   +1 more source

Chromatin organization of gammaherpesvirus latent genomes [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2010
The gammaherpesviruses are a subclass of the herpesvirus family that establish stable latent infections in proliferating lymphoid and epithelial cells. The latent genomes are maintained as multicopy chromatinized episomes that replicate in synchrony with the cellular genome.
Italo, Tempera, Paul M, Lieberman
openaire   +2 more sources

Signaling Activities of Gammaherpesvirus Membrane Proteins [PDF]

Journal of Virology, 2000
Members of the Herpesviridae family have large doublestranded DNA genomes and replicate in the nucleus of the host cell. Based on genomic organization and biological characteristics, herpesviruses are classified into three subfamilies: alpha, beta, and gamma (Fig. 1A). The gammaherpesviruses replicate and persist in lymphoid cells, but some are capable
B, Damania, J K, Choi, J U, Jung
openaire   +2 more sources

Oropharyngeal Shedding of Gammaherpesvirus DNA by Cats, and Natural Infection of Salivary Epithelium

Viruses, 2022
Felis catus gammaherpesvirus-1 (FcaGHV1), a novel candidate oncogenic virus, infects cats worldwide. Whether the oropharynx is a site of virus shedding and persistence, and whether oronasal carcinomas harbor FcaGHV1 nucleic acid were investigated.
Elizabeth C. Rose, Tiffany Y. Tse, Andrew W. Oates, Ken Jackson, Susanne Pfeiffer, Shannon L. Donahoe, Laura Setyo, Vanessa R. Barrs, Julia A. Beatty, Patricia A. Pesavento   +9 more
doaj   +1 more source