Guinea Pig X Virus Is a Gammaherpesvirus [PDF]
VirusesThe Guinea Pig X Virus (GPXV), a newly identified gammaherpesvirus, provides an opportunity to study viral evolution and host–virus dynamics. This study characterizes the GPXV genome and investigates its phylogenetic relationships and divergence from ...
Vy Ngoc Yen Truong +2 more
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Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host
Frontiers in Microbiology, 2016 Herpesviruses establish a chronic infection in the host characterized by intervals of lytic replication, quiescent latency, and reactivation from latency.
Laurie T Krug +3 more
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IL-22 promotes the establishment of chronic gammaherpesvirus infection by supporting the germinal center response. [PDF]
PLoS PathogensGammaherpesviruses, including human Epstein-Barr Virus (EBV) and Kaposi's Sarcoma-associated Herpesvirus (KSHV), establish lifelong latent infections that contribute to multiple cancers and Multiple Sclerosis.
Sheikh Tahir Majeed +2 more
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Gammaherpesvirus infection unveils exaggerated germinal center responses in an SR-BI-deficient host [PDF]
Journal of VirologyLipid metabolism has emerged as an important regulator of acute viral infections by affecting viral replication and the host immune response. In contrast, the role of host lipid metabolism during chronic viral infection has been less explored.
Damon L. Schmalzriedt +6 more
doaj +2 more sources
mBioGammaherpesviruses are species-specific, ubiquitous pathogens that establish lifelong infection in their hosts and are associated with cancers, including B cell lymphomas. Type I and II interferons (IFNs) are critical for the control of acute and chronic
Erika R. Johansen +8 more
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Long-Read Transcriptomics of Caviid Gammaherpesvirus 1: Compiling a Comprehensive RNA Atlas.
MSystemsCaviid gammaherpesvirus 1 (CaGHV-1), formerly known as the guinea pig herpes-like virus, is an oncogenic gammaherpesvirus with a sequenced genome but an as-yet uncharacterized transcriptome. Using nanopore long-read RNA sequencing, we annotated the CaGHV-
Dóra Tombácz +2 more
exaly +3 more sources
Detection of Felis catus Gammaherpesvirus 1 in Cats, but not Dogs, in Türkiye: Prevalence and Risk Factors. [PDF]
Vet Med SciThe current study was carried out to determine prevalence of Felis catus gammaherpesvirus 1 (FcaGHV1) in Turkish domestic cats and dogs and to investigate potential risk factors that are associated with the detection of FcaGHV1. FcaGHV1‐specific DNA was detected in 4 (7.4%, 95% confidence interval 0.4–14.4) of the 54 feline blood samples by TaqMan real‐
Şevik M.
europepmc +2 more sources
Pan‐gammaherpesvirus control via a broadly neutralising gB antibody [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Jiang Z, Li P, Xie C, Sun C.
europepmc +2 more sources
Packaging of viral microRNAs in gammaherpesvirus 68 [PDF]
, 2013 MicroRNAs are a characteristic of many herpesvirus genomes. These short, non-coding RNAs are capable of post-transcriptional regulation of target mRNAs. Recently, packaged miRNAs have been observed in purified virions of EBV and KSHV, gammaherpesviruses ...
Lutz, Jessica
core +5 more sources
The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection
Frontiers in Cellular and Infection Microbiology, 2023 Immediately after entry into host cells, viruses are sensed by the innate immune system, leading to the activation of innate antiviral effector mechanisms including the type I interferon (IFN) response and natural killer (NK) cells.
Viktoria Rex +7 more
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