Results 11 to 20 of about 7,401 (195)

Discovery of a Novel Bat Gammaherpesvirus [PDF]

mSphere, 2016
Zoonosis is the leading cause of emerging infectious diseases. In a recent article, R. S. Shabman et al. (mSphere 1[1]:e00070-15, 2016, http://dx.doi.org/10.1128/mSphere.00070-15 ) report the identification of a novel gammaherpesvirus in a cell line ...
Kurtis M. Host, Blossom Damania
doaj   +5 more sources

Gammaherpesvirus infections in equids: a review

Veterinary Medicine: Research and Reports, 2015
Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses.
MARENZONI, Maria Luisa, STEFANETTI, VALENTINA, DANZETTA, MARIA LUISA, Timoney, Peter Joseph   +3 more
core   +9 more sources

Gammaherpesvirus RNAs Come Full Circle [PDF]

mBio, 2019
After an adaptive immune response is mounted, gammaherpesviruses achieve persistence through the utilization of viral noncoding RNAs to craft a suitable host cell environment in an immunologically transparent manner. While gammaherpesvirus long noncoding RNAs (lncRNAs) and microRNAs have been recognized for some time and have been actively investigated,
Nathan A. Ungerleider, Scott A. Tibbetts, Rolf Renne, Erik K. Flemington   +3 more
openaire   +4 more sources

A novel porcine gammaherpesvirus

Virology, 2003
A novel porcine gammaherpesvirus was detected in the blood of domestic pigs by PCR. With degenerate-primer PCR and subsequent long-distance PCR approaches a 60-kbp genome stretch was amplified. Sequence analysis revealed the presence of the gammaherpesvirus ORFs 03 to 46 as well as a putative chemokine receptor and a v-bcl-2 gene.
Chmielewicz, Barbara, Goltz, Michael, Franz, Tatjana, Bauer, Cindy, Brema, Susanne, Ellerbrok, Heinz, Beckmann, Sabine, Rziha, Hanns-Joachim, Lahrmann, Karl-Heinz, Romero, Carlos, Ehlers, Bernhard   +10 more
openaire   +3 more sources

Gammaherpesvirus is nothing to sneeze at

Science Translational Medicine, 2017
Gammaherpesvirus protects against allergic asthma by inducing the replacement of alveolar macrophages.
Jennifer A. Philips
openaire   +2 more sources

Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host

Frontiers in Microbiology, 2016
Herpesviruses establish a chronic infection in the host characterized by intervals of lytic replication, quiescent latency, and reactivation from latency.
Laurie T Krug, Brandon Cieniewicz, Alexis Santana, Nana Minkah   +3 more
doaj   +2 more sources

Inhibition of Gammaherpesvirus Replication by RNA Interference [PDF]

Journal of Virology, 2003
ABSTRACT RNA interference (RNAi) is a conserved mechanism in which double-stranded, small interfering RNAs (siRNAs) trigger a sequence-specific gene-silencing process. Here we describe the inhibition of murine herpesvirus 68 replication by siRNAs targeted to sequences encoding Rta, an immediate-early protein known as an initiator of the lytic
Qingmei, Jia, Ren, Sun
openaire   +3 more sources

NF-κB Inhibits Gammaherpesvirus Lytic Replication [PDF]

Journal of Virology, 2003
ABSTRACT Nasopharyngeal carcinoma, Kaposi's sarcoma, and B-cell lymphomas are human malignancies associated with gammaherpesvirus infections. Members of this virus family are characterized by their ability to establish latent infections in lymphocytes. The latent viral genome expresses very few gene products.
Helen J, Brown, Moon Jung, Song, Hongyu, Deng, Ting-Ting, Wu, Genhong, Cheng, Ren, Sun   +5 more
openaire   +3 more sources

Apolipoprotein E selectively supports gammaherpesvirus replication in macrophages [PDF]

Journal of Virology
Gammaherpesviruses establish lifelong infections in over 90% of adults worldwide and contribute to the development of several cancers. Endogenous lipid synthesis pathways support lytic and latent life cycles of several gammaherpesviruses.
Damon L. Schmalzriedt, Carlie A. Aurubin, Cade R. Rahlf, Matthew A. Brown, Jordan M. Bobek, Philip T. Lange, Xander G. Bradeen, Daisy Sahoo, Vera L. Tarakanova   +8 more
doaj   +2 more sources

Evidence of an oncogenic gammaherpesvirus in domestic dogs

Virology, 2012
In humans, chronic infection with the gammaherpesvirus Epstein-Barr virus is usually asymptomatic; however some infected individuals develop hematological and epithelial malignancies. The exact role of EBV in lymphomagenesis is poorly understood partly because of the lack of clinically relevant animal models. Here we report the detection of serological
Huang, Shih-Hung, Kozak, Philip J., Kim, Jessica, Habineza-Ndikuyeze, Georges, Meade, Charles, Gaurnier-Hausser, Anita, Patel, Reema, Robertson, Erle, Mason, Nicola J.   +8 more
openaire   +3 more sources