Results 41 to 50 of about 44,477 (170)

The requirement of glycoprotein C (gC) for interindividual spread is a conserved function of gC for avian herpesviruses

Scientific Reports, 2021
We have formerly shown that glycoprotein C (gC) of Gallid alphaherpesvirus 2, better known as Marek’s disease (MD) alphaherpesvirus (MDV), is required for interindividual spread in chickens.
Widaliz Vega-Rodriguez, Huai Xu, Nagendraprabhu Ponnuraj, Haji Akbar, Taejoong Kim, Keith William Jarosinski   +5 more
doaj   +1 more source

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Frontiers in Immunology, 2022
Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to ...
Yue Yin, Jinglin Ma, Cliff Van Waesberghe, Bert Devriendt, Herman W. Favoreel   +4 more
doaj   +1 more source

Assembly and Egress of an Alphaherpesvirus Clockwork [PDF]

, 2017
All viruses produce infectious particles that possess some degree of stability in the extracellular environment yet disassemble upon cell contact and entry. For the alphaherpesviruses, which include many neuroinvasive viruses of mammals, these metastable virions consist of an icosahedral capsid surrounded by a protein matrix (referred to as the ...
openaire   +2 more sources

Isolation and Characterization of a Novel Alphaherpesvirus in Fruit Bats [PDF]

Journal of Virology, 2014
ABSTRACT Bats are known to harbor emerging RNA viruses. Recent studies have used high-throughput sequencing technology to identify various virus species, including DNA viruses that are harbored by bats; however, little is known about the nature of these potentially novel viruses.
Sasaki, Michihito, Setiyono, Agus, Handharyani, Ekowati, Kobayashi, Shintaro, Rahmadani, Ibenu, Taha, Siswatiana, Adiani, Sri, Subangkit, Mawar, Nakamura, Ichiro, Sawa, Hirofumi, Kimura, Takashi, Hutt-Fletcher, L.   +11 more
openaire   +3 more sources

Alphaherpesvirus in Pets and Livestock

Microorganisms
Herpesviruses are a group of DNA viruses capable of infecting multiple mammalian species, including humans. This review primarily summarizes four common alphaherpesviruses found in pets and livestock (feline, swine, canine, and bovine) in aspects such as epidemiology, immune evasion, and latency and reactivation.
Shu-Hui Duan, Ze-Min Li, Xue-Jie Yu, Dan Li   +3 more
openaire   +3 more sources

Examining the Role of Transmission of Chelonid Alphaherpesvirus 5 [PDF]

EcoHealth, 2017
Marine turtle fibropapillomatosis (FP) is a devastating neoplastic disease characterized by single or multiple cutaneous and visceral fibrovascular tumors. Chelonid alphaherpesvirus 5 (ChHV5) has been identified as the most likely etiologic agent. From 2010 to 2013, the presence of ChHV5 DNA was determined in apparently normal skin, tumors and swab ...
Chaves, Andrea, Aguirre, A. Alonso, Blanco-Peña, Kinndle, Moreira Soto, Andrés, Monge, Otto, Torres, Ana M., Soto-Rivas, José L., Lu, Yuanan, Chacón, Didiher, Fonseca, Luis, Jiménez, Mauricio, Gutierrez-Espeleta, Gustavo A., Lierz, Michael   +12 more
openaire   +4 more sources

2019 Colorado Alphaherpesvirus Latency Society symposium [PDF]

Journal of NeuroVirology, 2019
Meeting Report on the 9th Annual Symposium of the Colorado Alphaherpesvirus Latency Society (CALS) held on May 8-11, 2019, in Vail, CO.
Colleen Amanda, Mangold, Esteban A, Engel, Jeffery B, Ostler, Angus C, Wilson, Randall J, Cohrs   +4 more
openaire   +4 more sources

Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression

Microbiology Spectrum, 2023
Alphaherpesvirus infection is associated with attenuation of different aspects of the host innate immune response that is elicited to confine primary infections at the mucosal epithelia.
Nicolás Romero, Alexander Tishchenko, Ruth Verhamme, Shelly M. Wuerzberger-Davis, Cliff Van Waesberghe, Hans J. Nauwynck, Shigeki Miyamoto, Herman W. Favoreel   +7 more
doaj   +1 more source

CD49a expression defines a metabolically robust, cytokine‐biased liver NK cell subset in rhesus macaques during lentivirus infection

Immunology &Cell Biology, EarlyView.
Liver‐resident NK cells (CD49a+ NK cells) in rhesus macaques display distinct activating receptor and metabolic markers enhanced phenotype compared with hepatic NK cell subsets (CD49a−) in the liver. These cells exhibit heightened cytokine polyfunctionality with restrained cytotoxic responses upon mitogen stimulation in comparison with CD49a− NK cell ...
Andrew Hudson, Melissa Xin Yu Wong, Michael Verdolin, R Keith Reeves, Cordelia Manickam   +4 more
wiley   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, EarlyView.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source