Results 61 to 70 of about 13,742 (144)

Activation of ZBP1/RIPK3/MLKL‐Dependent Necroptosis by Pseudorabies Virus Restricts Viral Infection in BV2 Microglia Cells

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Pseudorabies (PR) virus (PRV), also known as suid herpesvirus 1, is an alphaherpesvirus that causes huge economic losses in the global swine industry. Necroptosis, a caspase‐independent programmed cell death, has been demonstrated to play an important role in regulating viral infections. Here, we showed that PRV infection triggered receptor‐interacting
Yiyu Liu, Haolin Li, Yu Dai, Jingyi Niu, Linhan Jiang, Jia Tang, Rendong Fang, Chao Ye, Linzhu Ren   +8 more
wiley   +1 more source

Modulation of apoptosis by caprine herpesvirus 1 infection in a neuronal cell line [PDF]

, 2013
Caprine herpesvirus type 1 (CpHV-1), like other members of the alpha subfamily of herpesviruses, establishes latent infections in trigeminal ganglion neurons.
Antonio Giordano, Carmen Pacilio, CIARCIA, ROBERTO, Claudio De Martinis, IOVANE, GIUSEPPE, Ivanna Kenez, Maria Valeria Puzio, MONTAGNARO, SERENA, Morena De Angelis, PAGNINI, UGO, SASSO, SIMONA, Silvia Boffo   +11 more
core   +1 more source

RACK1 Associates With STING to Promote Type I Interferon Activation and Inhibit Pseudorabies Virus Infection

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Pseudorabies virus (PRV), the causative agent of Aujeszky’s disease, leads to great economic losses on swine production worldwide. Receptor of activated protein kinase C 1 (RACK1) is initially known as a receptor for protein kinase C, and recent studies indicate that RACK1 can also play critical roles in various virus infections.
Yixuan Li, Yiyu Liu, Yu Dai, Jingyi Niu, Gang Li, Xiaoying Yu, Chao Wan, Rendong Fang, Chao Ye, Linzhu Ren   +9 more
wiley   +1 more source

Microbiological Profile of the Upper and Lower Respiratory Tract of Suckling and Weaned Dairy Calves with Acute Respiratory Disease

Veterinary Sciences
Bovine respiratory disease (BRD) is a significant global health issue in cattle farming, leading to substantial economic losses. This study analyzed the microbiological profiles of BRD outbreaks in nine dairy cattle herds in southern Brazil.
Alice Fernandes Alfieri, Juliana Torres Tomazi Fritzen, Carolina Yuka Yasumitsu, Amauri Alcindo Alfieri   +3 more
doaj   +1 more source

Comprehensive lung microbial gene and genome catalogs assist the mechanism survey of Mesomycoplasma hyopneumoniae strains causing pig lung lesions

iMeta, Volume 3, Issue 6, December 2024.
In this study, we utilized 744 metagenomic sequencing data from lower respiratory tract microbial samples of 675 well‐phenotyped pigs across five cohorts. From these, we constructed a microbial gene catalog containing 10,031,593 nonredundant genes and 356 metagenome‐assembled genomes (MAGs), which were further clustered into 256 species‐level genome ...
Jingquan Li, Fei Huang, Yunyan Zhou, Tao Huang, Xinkai Tong, Mingpeng Zhang, Jiaqi Chen, Zhou Zhang, Huipeng Du, Zifeng Liu, Meng Zhou, Yiwen Xiahou, Huashui Ai, Congying Chen, Lusheng Huang   +14 more
wiley   +1 more source

The Herpes Virus Fc Receptor gE-gI Mediates Antibody Bipolar Bridging to Clear Viral Antigens from the Cell Surface [PDF]

, 2014
The Herpes Simplex Virus 1 (HSV-1) glycoprotein gE-gI is a transmembrane Fc receptor found on the surface of infected cells and virions that binds human immunoglobulin G (hIgG).
Bjorkman, Pamela J., Farley, Alexander H., Fraser, Scott E., Lee, Terri, Ndjamen, Blaise   +4 more
core   +4 more sources

Histone deacetylase inhibitor boosts anticancer potential of fusogenic oncolytic vaccinia virus by enhancing cell–cell fusion

Cancer Science, Volume 115, Issue 2, Page 600-610, February 2024.
Fusogenic oncolytic vaccinia virus combined with histone deacetylase inhibitor trichostatin A induced strong antitumor effects through enhancing cell–cell fusion induction. Abstract Oncolytic viruses have two anticancer functions: direct oncolysis and elicitation of antitumor immunity. We previously developed a novel fusogenic oncolytic vaccinia virus (
Motomu Nakatake, Hajime Kurosaki, Takafumi Nakamura   +2 more
wiley   +1 more source

Designing a highly antigenic multi epitope subunit vaccine against Bovine alpha herpes virus 2 targeting glycoprotein B and H: A reverse vaccinology approach

Medicine in Omics
Bovine alphaherpesvirus 2 (BoHV-2), a major pathogen in cattle, belongs to the Herpesviridae family. In this work, we designed a vaccine against BoHV-2 using its envelope glycoprotein B (gB) and glycoprotein H.
Ali Khan, Sara Khan, Muhammad Rahiyab, Salman Khan, Zabih Ullah, Syed Shujait Ali   +5 more
doaj   +1 more source

The Role of the Equine Herpesvirus Type 1 (EHV-1) US3-Encoded Protein Kinase in Actin Reorganization and Nuclear Egress [PDF]

, 2016
The serine-threonine protein kinase encoded by US3 gene (pUS3) of alphaherpesviruses was shown to modulate actin reorganization, cell-to-cell spread, and virus egress in a number of virus species.
Alexandra Proft, Allen, Bart Spiesschaert, Maik Lehmann, Oppenheimer-Marks, Purves, Satoko Izume, Selina Taferner, Tischer, Walid Azab   +9 more
core   +2 more sources

Milk as a diagnostic fluid to monitor viral diseases in dairy cattle

Australian Veterinary Journal, Volume 102, Issue 1-2, Page 11-18, January-February 2024.
Background Infectious viral diseases in dairy cattle have substantial implications for milk production, quality and overall animal health. Diagnostic tools providing reliable results are crucial for effective disease control at the farm and industry level.
B Brito, P Hick
wiley   +1 more source