Results 91 to 100 of about 54,993 (202)

Factors determining the pattern of the variant Creutzfeldt-Jakob disease (vCJD) epidemic in the UK.

, 2003
Following the emergence of a new variant of Creutzfeldt-Jakob disease (vCJD) 6 years ago, and the gradual rise in clinical cases, there has been increased speculation regarding the overall magnitude of this epidemic in Great Britain.
Ghani, Azra C, Donnelly, Christl A, Anderson, Roy M, Ferguson, Neil M   +3 more
core   +1 more source

Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems

Macromolecular Rapid Communications, EarlyView.
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger, Rashmi Rashmi, Michael Karimov, Gideon Nölte, Markus Hafke, Ann‐Cathrin Schmitt, David Díaz‐Oviedo, Johannes Köbberling, Rainer Haag   +8 more
wiley   +1 more source

Covalently Immobilized Lignin–Xanthene Conjugates for Persistent Surface Photochemistry and Self‐Sterilizing Interfaces Under Ambient Visible Light

Macromolecular Rapid Communications, EarlyView.
Bio‐derived lignin–Eosin Y macromolecular networks are developed as visible‐light‐responsive self‐sterilizing coatings that generate reactive oxygen species without leaching. The spray‐coated photopolymerized surfaces exhibit durable antibacterial and antiviral activity under ambient light for extended periods, demonstrating a scalable and sustainable ...
Euna Oh, Surjith Kumaran, Sumin Han, Kiseok Lee, Hyerin Shin, Seokmin Oh, Dae‐Hong Ko, Hyo‐Jick Choi   +7 more
wiley   +1 more source

The epidemiology of variant Creutzfeldt-Jakob disease

, 2002
Variant Creutzfeldt-Jakob disease (vCJD) was identified as a new disease in 1996. It was linked to infection with the bovine spongiform encephalopathy (BSE) agent although the epidemiological evidence for this was not strong, but later strain typing ...
d' Huillard Aignaux, JN, S. N. Cousens, P. G. Smith, Smith, PG, J. N. Huillard d’Aignaux, Ghani, AC, Azra C. Ghani, Ward, HJT, R. G. Will, Cousens, SN, Will, RG, Huillard d'Aignaux, JN, H. J. T. Ward   +12 more
core   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

British Journal of Haematology, EarlyView.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed, Rattanaporn Praneetponkang, Potchaman Sittipaisankul, Chayada Thiengtavor, Suwathida Chumpuchanaphai, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Duncan R. Smith, Saovaros Svasti, Pornthip Chaichompoo   +11 more
wiley   +1 more source

Polarized Entry of Bovine Coronavirus in Epithelial Cells [PDF]

, 1995
Epithelial cells are highly polarized cells divided into an apical and a basolateral plasma membrane. The two domains are composed of a distinct set of proteins and lipids. Concerning virus infection of epithelial cells, the polarity of host cell receptor distribution defines the domain from which infection may be mediated.
B, Schultze, G, Herrler
openaire   +2 more sources

Serological Survey of Bovine Coronavirus in Korea [PDF]

Journal of Bacteriology and Virology, 2007
Bovine coronavirus (BCoV) is a causative agent of entero-pathogenic diarrhea in young calves and winter dysentery (WD) in adult cattle. In this study, we conducted a nationwide sero-epidemiological survey of BCoV infection in Korea. In total, 3,029 bovine sera collected between October and December 2005 were screened for the presence of antibodies ...
Dong-Kun Yang, Chang-Hee Kweon, Byoung-Han Kim, Jeong-Kyu Park, Byung-Jae So, Jae-Young Song   +5 more
openaire   +1 more source

First report of bovine rotavirus and bovine coronavirus seroprevalance in goats in Turkey

, 2007
In this study, bovine coronavirus (BCV) and bovine rotavirus (BRV) seroprevalances were detected by ELISA in 107 goat blood serum samples obtained from five different provinces of Northern Turkey.
Z. Yazici, D. Çakiroglu, H. Albayrak, Okur Gumusova   +3 more
core   +1 more source

Implications of BSE infection screening data for the scale of the British BSE epidemic and current European infection levels.

, 2002
The incidence of confirmed clinical cases of bovine spongiform encephalopathy (BSE) in Great Britain continues to decline, but the recent discovery of cases in previously unaffected countries (including Israel, Japan, Poland, Slovenia and Spain) has ...
Donnelly, Christl A, Ghani, Azra C, Anderson, Roy M, Ferguson, Neil M   +3 more
core   +1 more source

Heterologous protein secretion in Lactococcus lactis: a novel antigen delivery system

Brazilian Journal of Medical and Biological Research, 1999
Lactic acid bacteria (LAB) are Gram-positive bacteria and are generally regarded as safe (GRAS) organisms. Therefore, LAB could be used for heterologous protein secretion and they are good potential candidates as antigen delivery vehicles.
Langella P., Le Loir Y.
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