Results 71 to 80 of about 508,015 (216)

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang   +12 more
wiley   +1 more source

American Association of Bovine Practitioners 36th Annual Conference (2003): Part 2

open access: yes, 2003
Description and highlights of the 36th Annual Convention American Association of Bovine Practitioners (2003), information about, events, awards, receptions ...
Bovine Practitioners, American Association of
core   +1 more source

Bovine coronavirus in neonatal calf diarrhoea in Iran [PDF]

open access: yesVeterinary Medicine and Science, 2020
AbstractPartial gene sequencing for the bovine coronavirus at the World Genebank is available for many countries, which are distributed unevenly in five continents, but so far, no sequencing of strains has been recorded in Iran. One hundred ninety‐four stool samples from calves with diarrhoea less than one‐month old were collected from five different ...
Lotfollahzadeh, Samad   +4 more
openaire   +5 more sources

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

Establishment and application of multiplex droplet digital polymerase chain reaction assay for bovine enterovirus, bovine coronavirus, and bovine rotavirus

open access: yesFrontiers in Veterinary Science, 2023
Bovine enterovirus (BEV), bovine coronavirus (BCoV), and bovine rotavirus (BRV) are still the major worldwide concerns in the health care of cattle, causing serious economic losses in the livestock industry.
Junzhen Chen   +10 more
doaj   +1 more source

Index of Publications. The Bovine Practitioner 1985-1988 / Proceedings of the Annual Meetings 1985-1988

open access: yes, 1989
Author and suject indexes for the The Bovine Practitioner and the Proceedings of the Annual Meetings, 1985 ...
Bovine Practitioners, American Association of
core   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

open access: yesAdvanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv   +14 more
wiley   +1 more source

Index to Publications. The Bovine Practitioner 1967-1979 / Proceedings of the Annual Meetings 1973-1979

open access: yes, 1980
Author/Subject indexes for the Bovine Practitioner 1967-1979 and the Proceddings of the Annual Meetings 1973 ...
Bovine Practitioners, American Association of
core   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection

open access: yesViruses, 2022
Coronaviruses constitute a global threat to the human population; therefore, effective pan-coronavirus antiviral drugs are required to tackle future re-emerging virus outbreaks.
Ailyn C. Ramón   +12 more
doaj   +1 more source

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