Results 81 to 90 of about 590,983 (222)

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Index of Publications. The Bovine Practitioner 1985-1988 / Proceedings of the Annual Meetings 1985-1988

, 1989
Author and suject indexes for the The Bovine Practitioner and the Proceedings of the Annual Meetings, 1985 ...
Bovine Practitioners, American Association of
core   +1 more source

First detection of bovine coronavirus in Yak (Bos grunniens) and a bovine coronavirus genome with a recombinant HE gene

Journal of General Virology, 2019
The yak (Bosgrunniens) is a unique domestic bovine species that plays an indispensable role for herdsmen in the Qinghai-Tibet Plateau. Here, 336 diarrhoeic samples were collected from yaks on 29 farms in the Qinghai-Tibet Plateau from 2015 to 2017.
He, Qifu, Guo, Zijing, Zhang, Bin, Yue, Hua, Tang, Cheng   +4 more
openaire   +2 more sources

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection

Viruses, 2022
Coronaviruses constitute a global threat to the human population; therefore, effective pan-coronavirus antiviral drugs are required to tackle future re-emerging virus outbreaks.
Ailyn C. Ramón, George V. Pérez, Evelin Caballero, Mauro Rosales, Daylén Aguilar, Dania Vázquez-Blomquist, Yassel Ramos, Arielis Rodríguez-Ulloa, Viviana Falcón, María Pilar Rodríguez-Moltó, Ke Yang, Yasser Perera, Silvio E. Perea   +12 more
doaj   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Twenty-Eighth Annual Conference of the American Association of Bovine Practitioners: San Antonio, Texas, September 14-17, 1995

, 1995
Description of the the Annual Conference of the American Association of Bovine Practitioners (28th : 1995), officers, district news, events, awards, and other ...
American Association of Bovine Practitioners,
core   +1 more source

Antibody response to equine coronavirus in horses inoculated with a bovine coronavirus vaccine

Journal of Veterinary Medical Science, 2017
A vaccine for equine coronavirus (ECoV) is so far unavailable. Bovine coronavirus (BCoV) is antigenically related to ECoV; it is therefore possible that BCoV vaccine will induce antibodies against ECoV in horses. This study investigated antibody response to ECoV in horses inoculated with BCoV vaccine.
NEMOTO, Manabu, KANNO, Toru, BANNAI, Hiroshi, TSUJIMURA, Koji, YAMANAKA, Takashi, KOKADO, Hiroshi   +5 more
openaire   +3 more sources

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

Index of Publications. The Bovine Practitioner 1980-1984 / Proceedings of the Annual Meetings 1980-1984

, 2019
Author and Subject indexes for the Bovine Practitioner and the Proceedings of the Annual Meetings, 1980 ...
Bovine Practitioners, American Association of
core   +1 more source

Serum Antibodies to Bovine Coronavirus in Swedish Sheep [PDF]

Acta Veterinaria Scandinavica, 1999
Altogether 218 sheep sera from 40 flocks in different parts of Sweden were screened for antibodies to bovine coronavirus (BCV). Nineteen per cent of the sera were positive and there was a significantly higher frequency (p < 0.05) of at least one positive sample in flocks with more than 100 adult sheep than in smaller flocks.
M, Tråvén, U, Carlsson, A, Lundén, B, Larsson   +3 more
openaire   +2 more sources