Results 41 to 50 of about 1,537,014 (246)

Triple Immunochromatographic System for Simultaneous Serodiagnosis of Bovine Brucellosis, Tuberculosis, and Leukemia

Biosensors, 2019
An immunochromatographic test system has been developed for the simultaneous rapid multiplex serodiagnostics of bovine brucellosis, tuberculosis, and leukemia.
Lyubov V. Barshevskaya, Dmitriy V. Sotnikov, Anatoly V. Zherdev, Bekbolat B. Khassenov, Kayrat K. Baltin, Saule Z. Eskendirova, Kassym K. Mukanov, Kanatbek K. Mukantayev, Boris B. Dzantiev   +8 more
doaj   +1 more source

Multiple oncogenic viruses are present in human breast tissues before development of virus associated breast cancer

Infectious Agents and Cancer, 2017
Background Multiple oncogenic viruses including, mouse mammary tumor virus, bovine leukemia virus, human papilloma virus, and Epstein Barr virus, have been identified as separate infectious pathogens in human breast cancer. Here we demonstrate that these
James S. Lawson, Wendy K. Glenn
doaj   +1 more source

Detection of genetic material of causative agents of animal viral diseases in blood-sucking dipterans from the Tyumen Region

Российский паразитологический журнал, 2023
The purpose of the research is to test blood-sucking dipterans collected in the Tyumen Region for genetic material of viruses that cause dangerous diseases in live-stock animals.Materials and methods.
K. S. Krutko, A. G. Kinareikina, M. I. Serkova, E. A. Silivanova, O. A. Fedorova   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Effect of bovine leukemia virus on bovine mammary epithelial cells [PDF]

Virus Research, 2019
Bovine leukemia virus (BLV) is a retrovirus that infects cattle and is associated with an increase in secondary infections. The objective of this study was to analyze the effect of BLV infection on cell viability, apoptosis and morphology of a bovine mammary epithelial cell line (MAC-T), as well as Toll like receptors (TLR) and cytokine mRNA expression.
Martinez Cuesta, Lucia, Nieto Farías, María Victoria, Lendez, Pamela Anahí, Rowland, Raymond R. R., Sheahan, Maureen A., Cheuquepán Valenzuela, Felipe Andrés, Marin, Maia Solange, Dolcini, Guillermina Laura, Ceriani, Maria Carolina   +8 more
openaire   +3 more sources

Effect of dry pasteurized milk from cows infected with the leukemia virus on the development of malignant tumors

Ветеринария и кормление
The article presents experimental data on the reproduction of a muscular solid tumor in BALB/c mice and the study of dried milk from leukemia virus-infected cows after long-term pasteurization effect on the development of these tumors.
Laskavyy V.N. , Polyanina T.I., Laskavaya V.V. , Tarasenko T.N.   +3 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The effect of bovine BST2A1 on the release and cell-to-cell transmission of retroviruses

Virology Journal, 2017
Background Human BST2 (hBST2, also called Tetherin) is a host restriction factor that blocks the release of various enveloped viruses. BST2s from different mammals also possess antiviral activity.
Zhibin Liang, Yang Zhang, Jie Song, Hui Zhang, Suzhen Zhang, Yue Li, Juan Tan, Wentao Qiao   +7 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains [PDF]

, 2007
Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species.
Jean-Luc Duteyrat, Pignolet Béatrice, Stéphane Bertagnoli, Foucras Gilles, Béatrice Pignolet, Bertagnoli, Stéphane, Duteyrat, Jl, Aude Allemandou, Jacqueline Gelfi, Allemandou Aude, Bertagnoli Stéphane, Gelfi, Jacqueline, Foucras, Gilles, Duteyrat Jean-Luc, Gilles Foucras, Allemandou, Aude, Duteyrat, Jean-Luc, Pignolet, Béatrice, Gelfi Jacqueline   +18 more
core   +1 more source