Results 61 to 70 of about 61,257 (214)

Homologies entre les deux rétrovirus BLV et HTLV-1 et développement d’une nouvelle approche thérapeutique basée sur la levée de la latence virale [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2007
Homologies between BLV and HTLV-1 retroviruses and development of a novel therapeutic approach based on induction of viral expression. BLV (bovine leukemia virus) and HTLV-1 (human T-cell leukemia virus) are related retroviruses inducing leukemia (BLV ...
Nicolas Gillet, Luc Willems, Richard Kettmann   +2 more
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Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

Advanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin, Dilara Aylar, Archna Sharma, Ping Wang   +3 more
wiley   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Using a Herd Profile to Determine Age-Specific Prevalence of Bovine Leukemia Virus in Michigan Dairy Herds

Veterinary Medicine International, 2012
Enzootic bovine leukosis is a contagious disease of cattle caused by the retrovirus, bovine leukemia virus (BLV) and is the most common cause of malignant neoplasm in cattle.
Ronald J. Erskine, Paul C. Bartlett, Todd M. Byrem, Chelsea L. Render, Catherine Febvay, Jessica T. Houseman   +5 more
doaj   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Bovine leukemia virus discovered in human blood

BMC Infectious Diseases, 2019
Background Bovine leukemia virus (BLV) infection is widespread in cattle globally and is present in marketed beef and dairy products. Human infection with BLV has been reported in breast and lung cancer tissues and was significantly associated with ...
Gertrude C. Buehring, Anne DeLaney, HuaMin Shen, David L. Chu, Niema Razavian, Daniel A. Schwartz, Zach R. Demkovich, Michael N. Bates   +7 more
doaj   +1 more source

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

Chemistry – A European Journal, EarlyView.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis, Héloïse Uhl, Florence Niedergang, Jacques Fattaccioli, Blaise Dumat, Jean‐Maurice Mallet   +5 more
wiley   +1 more source

Detection of bovine leukemia virus in pasteurized milk from a number of industrial milk factories in Iran by Nested Polymerase Chain Reaction (PCR)

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī
Bovine leukemia virus (BLV) as the causative agent of enzootic bovine leukosis (EBL) is a retrovirus which is closely related to type 1 and 2 leukemia virus of human T cells and it is also considered as a possible cause of breast cancer in women.
Shobeir Yazdani Paraei, mohammad rahim hajikolayei, masoudreza Siefi abad shapori, Mohammad Nouri, Faramarz Beheshtifar, ُSima Şahinduran   +5 more
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