Results 61 to 70 of about 103,996 (284)

Detection and genotyping of bovine leukemia virus (BLV) in Vietnamese cattle

Journal of Veterinary Medical Science, 2020
Bovine leukemia virus (BLV) belongs to the genus, Deltaretrovirus of the family, Retroviridae and it is the causative agent of enzootic bovine leukosis. The prevalence of BLV in three provinces in the Red River Delta Region in the North of Vietnam, Hanoi,
D. Le, Nanako Yamashita-Kawanishi, M. Okamoto, S. V. Nguyen, N. Nguyen, K. Sugiura, T. Miura, T. Haga   +7 more
semanticscholar   +1 more source

Effect of BLV Infection on the Immune Function of Polymorphonuclear Neutrophil in Dairy Cows

Frontiers in Veterinary Science, 2021
Enzootic bovine leukemia is a late-onset, neoplastic infection caused by the bovine leukemia virus (BLV). BLV infection hinders the function of the immune system and induces other diseases, which negatively affects the performance and health of the ...
Guanxin Lv, Guanxin Lv, Hai Wang, Hai Wang, Jianfa Wang, Jianfa Wang, Shuai Lian, Shuai Lian, Rui Wu, Rui Wu   +9 more
doaj   +1 more source

Effects of Naturally Occurring Mutations in Bovine Leukemia Virus 5′-LTR and Tax Gene on Viral Transcriptional Activity

Pathogens, 2020
Bovine leukemia virus (BLV) is a deltaretrovirus infecting bovine B cells and causing enzootic bovine leucosis (EBL). The long terminal repeat (LTR) plays an indispensable role in viral gene expression. The BLV Tax protein acts as the main transactivator
A. Pluta, L. Willems, R. Douville, J. Kuźmak   +3 more
semanticscholar   +1 more source

Bovine Leukemia Virus Involvement In Enzootic Bovine Leukosis

, 1978
Publisher Summary Enzootic bovine leukosis is a contagious disease induced by bovine leukemia virus (BLV). It is a chronic disease that develops over a long period and can be schematically divided into three phases: (1) from birth to infection (some animals are already infected at birth), (2) from viral infection to tumorous transformation (a number ...
Burny, Arsène, Bex, Françoise, Chantrenne, Hubert, Cleuter, Yvette, Dekegel, Daniel, Ghysdael, Jacques, Kettmann, Richard, Leclercq, M, Leunen, Joseph, Mammerickx, Marc, Portetelle, Daniel   +10 more
openaire   +4 more sources

Effect of dry pasteurized milk from cows infected with the leukemia virus on the development of malignant tumors

Ветеринария и кормление
The article presents experimental data on the reproduction of a muscular solid tumor in BALB/c mice and the study of dried milk from leukemia virus-infected cows after long-term pasteurization effect on the development of these tumors.
Laskavyy V.N. , Polyanina T.I., Laskavaya V.V. , Tarasenko T.N.   +3 more
doaj   +1 more source

PRMT5 Is Required for Bovine Leukemia Virus Infection In Vivo and Regulates BLV Gene Expression, Syncytium Formation, and Glycosylation In Vitro

Viruses, 2020
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle and is closely related to human T-cell leukemia viruses.
Wlaa Assi, T. Hirose, S. Wada, R. Matsuura, S. Takeshima, Y. Aida   +5 more
semanticscholar   +1 more source

Effect of bovine leukemia virus on bovine mammary epithelial cells [PDF]

Virus Research, 2019
Bovine leukemia virus (BLV) is a retrovirus that infects cattle and is associated with an increase in secondary infections. The objective of this study was to analyze the effect of BLV infection on cell viability, apoptosis and morphology of a bovine mammary epithelial cell line (MAC-T), as well as Toll like receptors (TLR) and cytokine mRNA expression.
Guillermina Laura Dolcini, Maureen A. Sheahan, Felipe Cheuquepan Valenzuela, Felipe Cheuquepan Valenzuela, Lucia Martinez Cuesta, Lucia Martinez Cuesta, Maia Solange Marin, Maia Solange Marin, María Victoria Nieto Farias, Maria Carolina Ceriani, Raymond R. R. Rowland, Pamela Anahí Lendez   +11 more
openaire   +4 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Ablation of non-coding RNAs affects bovine leukemia virus B lymphocyte proliferation and abrogates oncogenesis

PLoS Pathogens, 2020
Viruses have developed different strategies to escape from immune response. Among these, viral non-coding RNAs are invisible to the immune system and may affect the fate of the host cell.
Roghaiyeh Safari, J. Jacques, Y. Brostaux, L. Willems   +3 more
semanticscholar   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source