Results 61 to 70 of about 109,818 (251)

Multicentric B-cell lymphoma in a pygmy goat [PDF]

open access: yes, 2016
A six-year-old, male pygmy goat was referred with a sudden onset of peripheral lymphadenopathy, which initially started as enlarged inguinal lymph nodes. Clinical examination showed swollen retropharyngeal, prescapular and inguinal lymph nodes. Serologic
Chiers, Koen   +6 more
core  

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

open access: yesAdvanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong   +13 more
wiley   +1 more source

Bovine leukemia virus: current perspectives

open access: yesVirus Adaptation and Treatment, 2017
Fil: Juliarena, Marcela Alicia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Tandil. Centro de Investigacion Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigacion Veterinaria de Tandil. Provincia de Buenos Aires. Gobernacion.
Juliarena, Marcela Alicia   +4 more
openaire   +5 more sources

Генетическое разнообразие вируса лейкоза крупного рогатого скота и его распространение в районах Республики Дагестан

open access: yesЮг России: экология, развитие
To study the spread of infection caused by the bovine leukemia virus in farms of the Republic of Dagestan.PCR diagnostics of 212 cattle blood samples collected in farms of the Kizlyarsky, Kumtorkalinsky and Tabasaransky districts was performed for the ...
D. A. Baboshko   +7 more
doaj   +1 more source

Effect of BLV Infection on the Immune Function of Polymorphonuclear Neutrophil in Dairy Cows

open access: yesFrontiers in Veterinary Science, 2021
Enzootic bovine leukemia is a late-onset, neoplastic infection caused by the bovine leukemia virus (BLV). BLV infection hinders the function of the immune system and induces other diseases, which negatively affects the performance and health of the ...
Guanxin Lv   +9 more
doaj   +1 more source

Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells [PDF]

open access: yes, 2015
MicroRNAs (miRNA) are a large family of small single-stranded RNA molecules found in all multicellular organisms. Early studies have been shown that miRNA are involved in cancer development and progression, and this role can be done by working as an ...
Hafizi, M.   +8 more
core   +2 more sources

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

open access: yesAdvanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen   +13 more
wiley   +1 more source

The theoretical and practical aspects of the recombinant antigens for the diagnosis of bovine leukemia production

open access: yesAnnals of Mechnikov's Institute, 2020
Introduction. Nowadays the problem of bovine leukemia (EBL) effective diagnosis in countries where EBL is registered and the disease-free areas remains actual.
O Shapovalova
doaj  

Bovine Leukemia Virus DNA in Human Breast Tissue

open access: yesEmerging Infectious Diseases, 2014
Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring   +5 more
doaj   +1 more source

Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging. [PDF]

open access: yes, 2015
We used the fluorescence ubiquitination-based cell cycle indicator (FUCCI) to monitor cell cycle arrest after treatment of FUCCI-expressing HeLa cells (FUCCI-HeLa) with a traditional Chinese medicine (TCM) herbal mixture LQ, previously shown to have anti-
Bouvet, Michael   +4 more
core   +2 more sources

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