Results 71 to 80 of about 103,996 (284)

MODERN METHODS AND EXPERIENCE OF STRUGGLE AGAINST LEUKEMIA OF CATTLE

В мире научных открытий, 2018
The article presents the main methods of diagnosis and control of the bovine leukemia virus currently used. The wide spread of the disease is due to a fairly easy transmission of the virus, the lack of early diagnosis, vaccination and treatment ...
Tatyana Vladimirovna Zubova, Vladimir Alexandrovich Pleshkov, Alexander Nikolaevich Mironov   +2 more
doaj   +1 more source

Functional and Pathogenic Roles of Retroviral Antisense Transcripts

Frontiers in Immunology, 2022
Exogenous retroviruses such as human immunodeficiency virus type 1 (HIV-1), human T-cell leukemia virus type 1 (HTLV-1) and bovine leukemia virus (BLV) can cause various diseases including immunodeficiency, inflammatory diseases and hematologic ...
Kosuke Toyoda, Masao Matsuoka
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Bovine Leukemia Virus DNA in Human Breast Tissue

Emerging Infectious Diseases, 2014
Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring, Hua Min Shen, Hanne M. Jensen, K. Yeon Choi, Dejun Sun, Gerard Nuovo   +5 more
doaj   +1 more source

Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein–Barr Virus (EBV)

Frontiers in Oncology, 2018
Background Although the risk factors for breast cancer are well established, namely female gender, early menarche and late menopause plus the protective influence of early pregnancy, the underlying causes of breast cancer remain unknown.
J. Lawson, Brian Salmons, W. Glenn
semanticscholar   +1 more source

Bovine Leukemia Virus in Bovine Aborted Fetuses

Journal of Leukemia, 2019
We investigated the infection of Bovine Leukemia Virus (BLV) related to other pathogens [Neospora caninum, Bovine Herpesvirus-1 (BoHV-1), Bovine Viral Diarrhea Virus (BVDV), and pathogenic bacteria] in 80 bovine aborted fetuses. The materials comprised whole fetuses, fetal organs, and placenta.
Rosa Maria Piatti, Alessandra Maria Dias Lacerda, Marcia Mayumi Fusuma, Vanessa Castro, Eliana Scarcelli Pinheiro, Liria Hiromi Okuda, Ricardo Harakava, Edviges Maristela Pituco, Kelly Cristina Santos Montanari, Aline Feola de Carvalho, Claudia Del Fava   +10 more
openaire   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Генетическое разнообразие вируса лейкоза крупного рогатого скота и его распространение в районах Республики Дагестан

Юг России: экология, развитие
To study the spread of infection caused by the bovine leukemia virus in farms of the Republic of Dagestan.PCR diagnostics of 212 cattle blood samples collected in farms of the Kizlyarsky, Kumtorkalinsky and Tabasaransky districts was performed for the ...
D. A. Baboshko, M. G. Daudova, P. Y. Achigecheva, K. A. Elfimov, D. K. Dandamaev, Z. R. Shakhbanova, A. V. Totmenin, N. M. Gashnikova   +7 more
doaj   +1 more source