Results 91 to 100 of about 454,290 (357)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Lipo-nutritional profile analysis of bovine milk, goat milk, and giant panda milk through untargeted lipidomics

open access: yesFood Science of Animal Products
Breast milk plays a crucial role in the growth of captive giant pandas, particularly lipids crucial to brain, retinal, and central nervous system development. This study aimed to analyze the lipid differences among bovine milk, goat milk, and giant panda
Qin Shu   +5 more
doaj   +1 more source

Bradykinin and Kininogens in Bovine Milk

open access: yesJournal of Biological Chemistry, 1989
Two peptides exhibiting kinin activity in an isolated rat uterus assay were purified from pasteurized skim bovine milk. The amino acid sequence of the more prominent peptide was found to be that of bradykinin. Partially purified kinin preparations were also obtained from N-tosyl-L-phenylalanyl chloromethyl ketone-treated trypsin digests of non-fat dry ...
W E, Wilson, L H, Lazarus, K B, Tomer
openaire   +2 more sources

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Comparative Analysis of Signature Lipid Structures in Canine and Feline Milk Compared with Bovine and Caprine Milk

open access: yesAnimals
This study systematically compared the lipidomes of canine, feline, bovine, and caprine milk. Feline milk contained the highest total lipid content (110.83 mg/mL), significantly exceeding that of canine (81.52 mg/mL), caprine (40.27 mg/mL), and bovine ...
Ying Chen   +7 more
doaj   +1 more source

New markers of bulk milk quality in relation to mastitis [PDF]

open access: yes, 2009
All dairy processors depend on a continuous supply of high-quality bulk milk from milk producers to be able to distribute liquid milk and dairy products.
Wickström, Erik
core  

Comparison of the effects of high and low milk-replacer feeding regimens on health and growth of crossbred dairy heifers [PDF]

open access: yes, 2019
Context: Pre-weaning growth in dairy heifers is highly dependent on the amount of milk fed. Both milk replacer (MR) and associated labour are costly, encouraging restricted milk rations and once-a-day feeding.
Johnson, Kate F.   +2 more
core   +2 more sources

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian   +5 more
wiley   +1 more source

β-casein gene polymorphism permits identification of bovine milk mixed with bubaline milk in mozzarella cheese

open access: yesGenetics and Molecular Biology, 2008
Mozzarella cheese is traditionally prepared from bubaline (Bubalus bubalis) milk, but product adulteration occurs mainly by addition of or full substitution by bovine milk.
Antonio R. Otaviano   +5 more
doaj   +1 more source

Kinin-like Activity in Bovine Milk

open access: yesJournal of Dairy Science, 1967
Abstract Cow's milk contains a protein which, when incubated with trypsin or snake venom, releases a material with the kinin-like ability to contract smooth muscle. This protein has been partially purified and was found to have a molecular weight of approximately 70,000.
B E, Leach, C R, Blalock, M J, Pallansch
openaire   +2 more sources

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