A Bovine Parainfluenza Virus Type 3 Vaccine Is Safe and Immunogenic in Early Infancy [PDF]
A phase 2 trial was conducted to assess in young infants the safety, tolerability, infectivity, and immunogenicity of multiple doses of an intranasal vaccine using bovine parainfluenza virus type 3 (bPIV3).One hundred ninety-two healthy 2-month-old infants were randomized 1 : 1 : 1 to receive 1x10(5) median tissue culture infective dose (TCID(50 ...
David P, Greenberg +16 more
openaire +2 more sources
Recombinant type 5 adenoviruses expressing bovine parainfluenza virus type 3 glycoproteins protect Sigmodon hispidus cotton rats from bovine parainfluenza virus type 3 infection [PDF]
Cotton rats were used to study the replication and pathogenesis of bovine parainfluenza virus type 3 (bPIV3) and to test the efficacy of the F and HN glycoproteins in modulating infection. In vitro cultures of cotton rat lung cells supported the growth of bPIV3 as shown by virus recovery, immunofluorescence, immunoprecipitation, and syncytium induction.
M M, Breker-Klassen +5 more
openaire +2 more sources
Seroprevalence and risk factor associated with respiratory viral pathogens in dual-purpose cattle of Aguachica, Rio de Oro, and La Gloria municipalities in Cesar department, Colombia [PDF]
Aim: The research was conducted to determine the seroprevalence and risk factor associated with respiratory viral pathogens in dual-purpose cattle of Aguachica, Rio de Oro and La Gloria municipalities in Cesar department, Colombia.
Juan Carlos Pinilla León +5 more
doaj +1 more source
/summary: Bovine Respiratory Disease (BRD) is a major cause of calfhood mortality. Bovine Respiratory Syncytial Virus (BRSV), Bovine Parainfluenza 3 Virus (BPIV3), Bovine Herpes Virus-1 (BHV-1), and Bovine Corona Virus (BCV) are major pathogens in BRD ...
Mark H. van Rooij +5 more
doaj +1 more source
Identification of two distinct bovine parainfluenza virus type 3 genotypes
The partial gene sequencing of the matrix (M) protein from seven clinical isolates of bovine parainfluenza virus type 3 (BPIV-3), and the complete sequencing of a representative isolate (Q5592) was completed in this study. Nucleotide sequence analysis was initiated because of the failure of in-house BPIV-3 RT-PCR methods to yield expected products for ...
Horwood, Paul Francis +2 more
openaire +5 more sources
Antigenic variation of human and bovine parainfluenza virus type 3 strains
Three human and six bovine parainfluenza virus type 3 (PIV3) strains were examined by the use of 60 monoclonal antibodies (MAbs). Fifty-three MAbs to the human C243 strain were directed against six, four, nine and seven epitopes of the haemagglutinin-neuraminidase (HN), fusion (F), nucleocapsid (N) and matrix proteins, respectively.
E, Klippmark +3 more
openaire +2 more sources
Seroprevalence of some bovine viral respiratory diseases among non vaccinated cattle in Saudi Arabia
Aim: Four viral pathogens, bovine viral diarrhea virus (BVDV), and bovine herpes virus type 1 (BHV-1), bovine parainfluenza type 3 virus (PI-3V), bovine respiratory syncytial virus (BRSV) are mainly associated with bovine respiratory diseases that cause ...
Mohamed Abd El Fatah Mahmoud +3 more
doaj +1 more source
Indirect detection of respiratory viruses responsible for respiratory disease in sheep
Respiratory disease in sheep is an important disease in sheep flocks, in which viruses are categorized as primary etiological agents. It is responsible for elevated economic losses in sheep production and new data about its occurrence and the ...
Mariane Ferreira Franco +6 more
doaj
Coinfection of some respiratory viruses in cattle: An abattoir study
To investigate the existence of bovine viral diarrhoea virus (BVDV), parainfluenza virus 3 (PIV-3) and respiratory syncytial virus (RSV) as well as its coinfections, a total of 420 pneumonic lung tissue samples were collected from slaughterhouses in ...
Intisar K. Saeed +4 more
doaj +1 more source
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins +8 more
wiley +1 more source

