Results 81 to 90 of about 243,194 (292)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes [PDF]

, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Alonso, S., Balasch, M., Enjuanes, L., Izeta, A., Moormann, R.J.M., Plana Duran, J., Reimann, I., Sola, I., Teifke, J.P.   +8 more
core   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

In Vitro Activity and Rodent Efficacy of Clinafloxacin For Bovine and Swine Respiratory Disease

Frontiers in Microbiology, 2013
Clinafloxacin is a broad-spectrum fluoroquinolone that was originally developed and subsequently abandoned in the late 1990s as a human health antibiotic for respiratory diseases. The purpose of this study was to investigate the activity of clinafloxacin
Michael T Sweeney, Rebecca eQuesnell, Raksha eTiwari, Mary eLeMay, Jeffrey eWatts   +4 more
doaj   +1 more source

An in vitro study of the replication, morphology and DNA base composition of Mycoplasma ovipneumoniae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, New Zealand [PDF]

, 1977
Mycoplasma ovipneumoniae can almost invariably be isolated from the lungs of sheep with chronic pneumonia, which is a prevalent disease in New Zealand hoggets.
Major, Robert Malcolm
core  

Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus [PDF]

, 2019
Influenza C virus (ICV) was first identified in humans and swine, but recently also in cattle, indicating a wider host range and potential threat to both the livestock industry and public health than was originally anticipated.
He, Wanting, Li, Gairu, Su, Shuo, Veit, Michael, Wang, Congcong, Wen, Baiqing, Xu, Qiuhua, Zhang, Letian, Zhang, Wenyan, Zhang, Xu, Zhou, Jiyong   +10 more
core   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Establishment of a Real-Time Reverse Transcription Recombinase-Aided Isothermal Amplification (qRT-RAA) Assay for the Rapid Detection of Bovine Respiratory Syncytial Virus

Veterinary Sciences
Background: Bovine respiratory syncytial virus (BRSV) is a significant cause of bovine respiratory disease, resulting in significant losses to the cattle industry. For rapid detection of BRSV, a real-time recombinase-aided isothermal amplification assay (
Guanxin Hou, Siping Zhu, Hong Li, Chihuan Li, Xiaochen Liu, Chao Ren, Xintong Zhu, Qiumei Shi, Zhiqiang Zhang   +8 more
doaj   +1 more source

Modelling aspects of oviduct fluid formation in vitro [PDF]

, 2016
© 2017 Society for Reproduction and Fertility. Oviduct fluid is the microenvironment that supports early reproductive processes including fertilisation, embryo cleavage and genome activation.
Arnold, Georg, Arnold, Georg J., Froehlich, Thomas, Fröhlich, Thomas, Leese, Henry, Leese, Henry J., Sathyapalan, Thozhukat, Simintiras, Constantine A., Sturmey, Roger, Sturmey, Roger G., Ulbrich, Susanne, Ulbrich, Susanne E.   +11 more
core   +2 more sources

Bovine Respiratory Disease virtual symposium [PDF]

Animal Health Research Reviews, 2020
Christopher C L, Chase, Amelia R, Woolums   +1 more
openaire   +2 more sources