Results 91 to 100 of about 138,768 (302)

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Identification of Risk Factors Associated with Treatment for BRD in Beef Calves Within the First 60 Days After Arrival at Fattening Operations in Northwestern Italy Beef Calves

Veterinary Sciences
Bovine respiratory disease (BRD) impacts beef cattle health and farming systems. To better understand the BRD predisposing factors, a study was conducted in northwest Italy on a population of 26 batches (760 animals) of beef cattle imported from France ...
Isabella Nicola, Giuliano Borriello, Edoardo Ramacciotti, Giovanni Gallina, Maurizio Beltramo, Claudio Bellino   +5 more
doaj   +1 more source

THE PREVALENCE OF TEN PATHOGENS DETECTED BY A REAL-TIME PCR METHOD IN NASAL SWAB SAMPLES COLLECTED FROM LIVE CATTLE WITH RESPIRATORY DISEASE

Slovenian Veterinary Research, 2017
Respiratory diseases often correspond to primary infections with different pathogens of cattle, causing heavy economic losses in young stock and breeding herds.
Tomislav Paller, Peter Hostnik, Ivan Toplak, Milan Pogačnik   +3 more
doaj   +1 more source

Laboratory and Postmortem Diagnosis of Bovine Respiratory Disease

Veterinary Clinics of North America: Food Animal Practice, 2012
Pathologic and laboratory investigations are essential when identification of the specific cause of bovine respiratory disease is needed. Considerations for planning a diagnostic investigation include the goals of the inquiry, the potential impact of the diagnosis, the plausible causes based on the clinical and epidemiologic appearance, and the ...
Caswell, Jeff L., Hewson, Joanne, Slavić, Ðurđa, DeLay, Josepha, Bateman, Ken   +4 more
openaire   +2 more sources

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex. [PDF]

, 2015
Bovine respiratory disease complex (BRDC) is an important cause of mortality and morbidity in cattle; costing the dairy and beef industries millions of dollars annually, despite the use of vaccines and antibiotics.
Toaff-Rosenstein, Rachel, Jeremy F Taylor, McEligot, Heather A, Mark L Anderson, Neibergs, Holly, Taylor, Jeremy, Heather A. McEligot (827039), Matt X. Shao (827040), James Womack, Taylor, Jeremy F, Anderson, Mark L, Matt X Shao, Rachel Toaff-Rosenstein (762239), Holly L Neibergs, Mark L. Anderson (827038), James Womack (78963), Gershwin, Laurel, Laurel J. Gershwin (653896), Holly L. Neibergs (127865), Laurel J Gershwin, Alison L. Van Eenennaam (242082), Heather A McEligot, Gershwin, Laurel J, Rachel Toaff-Rosenstein, Van Eenennaam, Alison L, Alison L Van Eenennaam, Bovine Respiratory Disease Complex Coordinated Agricultural Project Research Team, Alison L. Van Eenennaam, Shao, Matt X, Jeremy F. Taylor (179789), Shao, Matt, Anderson, Mark, Womack, James, Neibergs, Holly L, McEligot, Heather   +34 more
core   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

ROS‐Responsive Nanobubbles for Dual‐Enhanced Ultrasound and Magnetic Resonance Imaging of Tumor Oxidative Stress

Advanced Science, EarlyView.
We report the development of biotinylated PEGylated bilirubin‐coated perfluoropentane (bt‐PEG‐BR@PFP) nanobubbles, a novel class of ROS‐activatable and dual‐modality contrast agents that amplify both ultrasound (US) and magnetic resonance imaging (MRI) signals in response to elevated ROS.
Wonsik Jung, Youngju Son, Dong Yun Lee, Youngeun Jeon, Muhammad Asaddudin, Sung‐Hong Park, Sangyong Jon   +6 more
wiley   +1 more source

A cohort study of bovine tuberculosis in cattle in South West England [PDF]

Farm, cattle group and individual bovine risk factors for bovine tuberculosis (bTB) in cattle herds in the South West of England were explored. A cohort study using 148 well characterised cattle herds was conducted in SW England 2001-2004. The study was
Ramírez Villaescusa, Ana
core  

Bovine Parainfluenza Virus 3 and Bovine Respiratory Syncytial Virus: Dominant Viral Players in Bovine Respiratory Disease Complex among Serbian Cattle

Animals
Bovine respiratory disease complex, a complex respiratory ailment in cattle, results from a combination of viral and bacterial factors, compounded by environmental stressors such as overcrowding, transportation, and adverse weather conditions. Its impact
Vesna Milićević, Sofija Šolaja, Dimitrije Glišić, Milan Ninković, Bojan Milovanović, Milan Đorđević, Snežana Ristevski, Filip Spasojević, Miroljub Dačić   +8 more
doaj   +1 more source