Eliminating Spiked Bovine Spongiform Encephalopathy Agent Activity from Heparin [PDF]
Emerging Infectious Diseases, 2020 US manufacturers, concerned about bovine spongiform encephalopathy (BSE), ceased marketing bovine heparin in the 1990s. Recent short supplies of safe porcine heparin suggest that reintroducing bovine heparin might benefit public health.
Cyrus Bett +5 more
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Experimental Bovine Spongiform Encephalopathy in Squirrel Monkeys: The Same Complex Proteinopathy Appearing after Very Different Incubation Times [PDF]
Pathogens, 2022 Incubation periods in humans infected with transmissible spongiform encephalopathy (TSE) agents can exceed 50 years. In humans infected with bovine spongiform encephalopathy (BSE) agents, the effects of a “species barrier,” often observed when TSE ...
Pedro Piccardo +7 more
doaj +2 more sources
Biodegradation of bovine spongiform encephalopathy prions in compost [PDF]
Scientific Reports, 2022 To reduce the transmission risk of bovine spongiform encephalopathy prions (PrPBSE), specified risk materials (SRM) that can harbour PrPBSE are prevented from entering the feed and food chains.
Shanwei Xu +7 more
doaj +2 more sources
Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy. [PDF]
PLoS ONE, 2015 European red deer (Cervus elaphus elaphus) are susceptible to the agent of bovine spongiform encephalopathy, one of the transmissible spongiform encephalopathies, when challenged intracerebrally but their susceptibility to alimentary challenge, the ...
Mark P Dagleish +15 more
doaj +2 more sources
Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE). [PDF]
PLoS ONE, 2015 Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant Creutzfeldt-Jakob disease (vCJD).
Dongseob Tark +8 more
doaj +2 more sources
Administration of L-Type Bovine Spongiform Encephalopathy to Macaques to Evaluate Zoonotic Potential [PDF]
Emerging Infectious DiseasesWe administered L-type bovine spongiform encephalopathy prions to macaques to determine their potential for transmission to humans. After 75 months, no clinical symptoms appeared, and prions were undetectable in any tissue by Western blot or ...
Morikazu Imamura +9 more
doaj +2 more sources
Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle [PDF]
Emerging Infectious Diseases, 2017 To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest
Hiroyuki Okada +7 more
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Bovine spongiform encephalopathy [PDF]
Veterinary Record, 1988 T A, Holt, J, Phillips
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Experimental bovine spongiform encephalopathy infection in rabbits [PDF]
BIO Web of Conferences, 2023 The aim of our work was to determine the sensitivity of rabbits to the C-BSE pathogen in the first passage, to obtain a laboratory model on rabbits to study the C-BSE pathogen.
Nadtochey Grigory +2 more
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Animal prion diseases: A review of intraspecies transmission [PDF]
Open Veterinary Journal, 2021 Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher ...
Mauro Julián Gallardo +1 more
doaj +1 more source