Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]
, 2008 The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Andréoletti +43 more
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Variability in disease phenotypes within a single PRNP genotype suggests the existence of multiple natural sheep scarpie strains within Europe [PDF]
, 2010 Variability of pathological phenotypes within classical sheep scrapie cases has been reported for some time, but in many instances it has been attributed to differences in the PRNP genotype of the host.
Acín, C. +12 more
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Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
Emerging Infectious Diseases, 2012 We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue.
Nadine Mestre-Francés +7 more
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BSE case associated with prion protein gene mutation. [PDF]
PLoS Pathogens, 2008 Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy (TSE) of cattle and was first detected in 1986 in the United Kingdom. It is the most likely cause of variant Creutzfeldt-Jakob disease (CJD) in humans.
Jürgen A Richt, S Mark Hall
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Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
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Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction
Pathogens, 2013 Kuru, the first human transmissible spongiform encephalopathy was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). In this review, I briefly summarize the history of this seminal discovery along its epidemiology, clinical picture ...
Pawel P. Liberski
doaj +1 more source
BSE crisis and food safety regulation: a comparison of the UK and Germany [PDF]
, 2007 The BSE crisis represents one of the worst policy disasters experienced by a UK government in recent years. In material terms, it led to the slaughter of 3.3 million cattle and an estimated economic loss of £3.7 billion.
Asenova, D., Beck, M., Kewell, B.
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Molecular Dynamics Studies on the Buffalo Prion Protein [PDF]
, 2015 It was reported that buffalo is a low susceptibility species resisting to prion diseases, which are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of species.
Chatterjee, Subhojyoti +2 more
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Genetics of Prion Disease in Cattle
Bioinformatics and Biology Insights, 2015 Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk.
Brenda M. Murdoch, Gordon K. Murdoch
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Hypotheses on the origin and transmission of BSE
Veterinární Medicína, 2001 EC Health & Consumer Protection Directorate-General recently published an important document based on papers and reviews discussed by members of TSE/BSE ad hoc group.
K. Hruška
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