Results 61 to 70 of about 21,465 (231)
The Molecular Pathology of Prion Diseases [PDF]
, 2004 Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen +2 more
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People and Nature, EarlyView.Abstract Pastoral practices remain a widespread economic activity across European mountain regions. However, the viability of this activity may be threatened by the recovery of large wild vertebrates associated with passive rewilding, leading to the so‐called human–wildlife conflicts.
P. Acebes +4 more
wiley +1 more source
PLoS ONE, 2012 Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform ...
Kurt C VerCauteren +4 more
doaj +1 more source
Methods for differentiating prion types in food-producing animals [PDF]
, 2015 Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrPSc).
Gough, Kevin C. +3 more
core +2 more sources
Wildlife Letters, EarlyView.We examined changes in perceived risks associated with chronic wasting disease (CWD) and perceived trust in wildlife agencies over time across 10 studies in eight states. Results indicated that perceived risks to both deer and humans declined the longer the disease had been in a state. Results also indicated that agency trust evaluations were positive,
Jerry J. Vaske, Craig A. Miller
wiley +1 more source
Significant differences in incubation times in sheep infected with bovine spongiform encephalopathy result from variation at codon 141 in the PRNP gene [PDF]
, 2012 The susceptibility of sheep to prion infection is linked to variation in the PRNP gene, which encodes the prion protein. Common polymorphisms occur at codons 136, 154 and 171.
Blanco, A. R. A. +8 more
core +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
Brain Pathology, EarlyView.We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
JCMS: Journal of Common Market Studies, EarlyView.Abstract Trust in regulatory regimes is essential for democratic legitimacy and regulatee compliance. This is particularly relevant in multilevel systems such as the European Union. This study examines the interplay of individual‐ and country‐level factors that contribute to stakeholder trust in the European Food Safety Authority (EFSA).
Jana Gómez Díaz
wiley +1 more source
Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy. [PDF]
PLoS ONE, 2017 Prions are amyloid-forming proteins that cause transmissible spongiform encephalopathies through a process involving conversion from the normal cellular prion protein to the pathogenic misfolded conformation (PrPSc).
Soyoun Hwang +2 more
doaj +1 more source
Emerging infectious diseases: coping with uncertainty [PDF]
, 2009 The world’s scientific community must be in a state of constant readiness to address the threat posed by newly emerging infectious diseases. Whether the disease in question is SARS in humans or BSE in animals, scientists must be able to put into action ...
Cummings, L
core +1 more source