Results 11 to 20 of about 7,307 (155)

Strain Traits of Intracranially Administered L-Type Bovine Spongiform Encephalopathy Prions Are not Significantly Modified During Intraspecies Transmission in Cynomolgus Monkeys. [PDF]

open access: yesMicrobiol Immunol
ABSTRACT Among the three prion strains of bovine spongiform encephalopathy (BSE), classical BSE (C‐BSE) prions are known causative agents of variant Creutzfeldt–Jakob disease. By contrast, human infections with L‐type (L‐) or H‐type (H‐) BSE prions have not been reported.
Hagiwara K   +8 more
europepmc   +2 more sources

BSE-associated Prion-Amyloid Cardiomyopathy in Primates

open access: yesEmerging Infectious Diseases, 2013
Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease,
Susanne Krasemann   +11 more
doaj   +1 more source

RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE

open access: yesBMC Research Notes, 2021
Objective The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of
Alessandra Favole   +17 more
doaj   +1 more source

Spongiform Encephalopathy in a Miniature Zebu

open access: yesEmerging Infectious Diseases, 2006
The first case of spongiform encephalopathy in a zebu (Bos indicus) was identified in a zoo in Switzerland. Although histopathologic and immunohistochemical analyses of the central nervous system indicated a diagnosis of bovine spongiform encephalopathy (
Torsten Seuberlich   +8 more
doaj   +1 more source

Jellyfish Collagen: A Biocompatible Collagen Source for 3D Scaffold Fabrication and Enhanced Chondrogenicity

open access: yesMarine Drugs, 2021
Osteoarthritis (OA) is a multifactorial disease leading to degeneration of articular cartilage, causing morbidity in approximately 8.5 million of the UK population.
Zara Ahmed   +6 more
doaj   +1 more source

Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie

open access: yesEmerging Infectious Diseases, 2011
Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation.
Laura Pirisinu   +9 more
doaj   +1 more source

Elaboration of a new framework for fine-grained epidemiological annotation

open access: yesScientific Data, 2022
Measurement(s) Precision/Recall • Annotator aggreement Technology Type(s) Expert annotation • Kappa’s coefficient • Natural Language Processing Sample Characteristic - Organism Animal • African swine fever virus • Avian influenza • Foot-and-mouth disease
Sarah Valentin   +5 more
doaj   +1 more source

An overview of animal prion diseases

open access: yesVirology Journal, 2011
Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj   +1 more source

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model

open access: yesEmerging Infectious Diseases, 2007
Transmissible mink encepholapathy (TME) is a foodborne transmissible spongiform encephalopathy (TSE) of ranch-raised mink; infection with a ruminant TSE has been proposed as the cause, but the precise origin of TME is unknown.
Thierry G.M. Baron   +4 more
doaj   +1 more source

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