Results 21 to 30 of about 7,307 (155)

Conversion of the BASE prion strain into the BSE strain: the origin of BSE?

PLoS Pathogens, 2007
Atypical neuropathological and molecular phenotypes of bovine spongiform encephalopathy (BSE) have recently been identified in different countries.
Raffaella Capobianco, Cristina Casalone, Silvia Suardi, Michela Mangieri, Claudia Miccolo, Lucia Limido, Marcella Catania, Giacomina Rossi, Giuseppe Di Fede, Giorgio Giaccone, Maria Grazia Bruzzone, Ludovico Minati, Cristiano Corona, Pierluigi Acutis, Daniela Gelmetti, Guerino Lombardi, Martin H Groschup, Anne Buschmann, Gianluigi Zanusso, Salvatore Monaco, Maria Caramelli, Fabrizio Tagliavini   +21 more
doaj   +1 more source

Candidate Cell Substrates, Vaccine Production, and Transmissible Spongiform Encephalopathies

Emerging Infectious Diseases, 2011
Transmissible spongiform encephalopathy (TSE) agents have contaminated human tissue–derived medical products, human blood components, and animal vaccines.
Pedro Piccardo, Larisa Cervenakova, Irina Vasilyeva, Oksana Yakovleva, Igor Bacik, Juraj Cervenak, Carroll McKenzie, Lubica Kurillova, Luisa Gregori, Kitty Pomeroy, David M. Asher   +10 more
doaj   +1 more source

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Emerging Infectious Diseases, 2012
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue.
Nadine Mestre-Francés, Simon Nicot, Sylvie Rouland, Anne-Gaëlle Biacabe, Isabelle Quadrio, Armand Perret-Liaudet, Thierry Baron, Jean-Michel Verdier   +7 more
doaj   +1 more source

Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction

Pathogens, 2013
Kuru, the first human transmissible spongiform encephalopathy was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). In this review, I briefly summarize the history of this seminal discovery along its epidemiology, clinical picture ...
Pawel P. Liberski
doaj   +1 more source

BSE case associated with prion protein gene mutation. [PDF]

PLoS Pathogens, 2008
Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy (TSE) of cattle and was first detected in 1986 in the United Kingdom. It is the most likely cause of variant Creutzfeldt-Jakob disease (CJD) in humans.
Jürgen A Richt, S Mark Hall
doaj   +1 more source

Genetics of Prion Disease in Cattle

Bioinformatics and Biology Insights, 2015
Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk.
Brenda M. Murdoch, Gordon K. Murdoch
doaj   +1 more source

Hypotheses on the origin and transmission of BSE

Veterinární Medicína, 2001
EC Health & Consumer Protection Directorate-General recently published an important document based on papers and reviews discussed by members of TSE/BSE ad hoc group.
K. Hruška
doaj   +1 more source

Isolation of Prion with BSE Properties from Farmed Goat

Emerging Infectious Diseases, 2011
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that include variant Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE) in cattle.
John Spiropoulos, Richard Lockey, Rosemary E. Sallis, Linda A. Terry, Leigh Thorne, Thomas M. Holder, Katy E. Beck, Marion M. Simmons   +7 more
doaj   +1 more source

The new variant of the Creutzfeldt-Jakob disease accounts for no relative increase of the Creutzfeldt-Jakob disease mortality rate in the United Kingdom; this fits ill with the new variant being the consequence of consumption of food infected with the agent of Bovine Spongiform Encephalopathy

BMC Public Health, 2003
Background A new variant of Creutzfeldt-Jakob disease was described in the United Kingdom. It is often claimed that it is caused by consumption of food infected with the agent of bovine spongiform encephalopathy.
Hénaut Alain, Laprevotte Ivan
doaj   +1 more source

Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes. [PDF]

PLoS Pathogens, 2008
The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in ...
Guerino Lombardi, Cristina Casalone, Antonio D' Angelo, Daniela Gelmetti, Gloria Torcoli, Ilaria Barbieri, Cristiano Corona, Elisa Fasoli, Alessia Farinazzo, Michele Fiorini, Matteo Gelati, Barbara Iulini, Fabrizio Tagliavini, Sergio Ferrari, Maria Caramelli, Salvatore Monaco, Lorenzo Capucci, Gianluigi Zanusso   +17 more
doaj   +1 more source