Results 61 to 70 of about 7,307 (155)

Transmission of Atypical Bovine Prions to Mice Transgenic for Human Prion Protein

open access: yesEmerging Infectious Diseases, 2008
To assess risk for cattle-to-human transmission of prions that cause uncommon forms of bovine spongiform encephalopathy (BSE), we inoculated mice expressing human PrP Met129 with field isolates.
Vincent Béringue   +6 more
doaj   +1 more source

Chemical Approaches for Array Based Detection of Amyloids

open access: yesAdvanced Sensor Research, Volume 4, Issue 11, November 2025.
Amyloids are protein aggregates with both pathological and functional roles. Their detection is challenged by structural polymorphism, isoform diversity, and dynamic aggregation behavior. This review presents chemical array‐based sensing strategies that address these complexities, emphasizing fluorescence and colorimetric methods, alongside ...
Paulo M. Simon, Yijia Xu, Amandeep Kaur
wiley   +1 more source

Improving Clinical Diagnosis of Transmissible Spongiform Encephalopathies in Sheep: Which Signs Are Important?

open access: yesAnimals
Scrapie is a notifiable transmissible spongiform encephalopathy (TSE) in sheep that relies on clinical examinations for reporting suspects. A short examination protocol was used in 1002 sheep to define clinical markers suggestive of scrapie.
Timm Konold, Laura J. Phelan
doaj   +1 more source

Sheep Feed and Scrapie, France

open access: yesEmerging Infectious Diseases, 2005
Scrapie is a small ruminant, transmissible spongiform encephalopathy (TSE). Although in the past scrapie has not been considered a zoonosis, the emergence of bovine spongiform encephalopathy, transmissible to humans and experimentally to sheep, indicates
Sandrine Philippe   +5 more
doaj   +1 more source

Molecular Typing of Protease-Resistant Prion Protein in Transmissible Spongiform Encephalopathies of Small Ruminants, France, 2002–2009

open access: yesEmerging Infectious Diseases, 2011
The agent that causes bovine spongiform encephalopathy (BSE) may be infecting small ruminants, which could have serious implications for human health. To distinguish BSE from scrapie and to examine the molecular characteristics of the protease-resistant ...
Johann Vulin   +4 more
doaj   +1 more source

Bovine Spongiform Encephalopathy Infectivity in Greater Kudu (Tragelaphus strepsiceros)

open access: yesEmerging Infectious Diseases, 2004
Of all the species exposed naturally to the bovine spongiform encephalopathy (BSE) agent, the greater kudu (Tragelaphus strepsiceros), a nondomesticated bovine from Africa, appears to be the most susceptible to the disease.
Andrew A. Cunningham   +5 more
doaj   +1 more source

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy. [PDF]

open access: yesPLoS Pathog, 2022
Otero A   +12 more
europepmc   +1 more source

Rapid Typing of Transmissible Spongiform Encephalopathy Strains with Differential ELISA

open access: yesEmerging Infectious Diseases, 2008
The bovine spongiform encephalopathy (BSE) agent has been transmitted to humans, leading to variant Creutzfeldt-Jakob disease. Sheep and goats can be experimentally infected by BSE and have been potentially exposed to natural BSE; however, whether BSE ...
Stéphanie Simon   +12 more
doaj   +1 more source

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