Results 81 to 90 of about 100,889 (274)

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Between‐country differences in the psychosocial profiles of British cattle farmers

Veterinary Record, EarlyView.
Abstract Background Psychosocial factors are important for the uptake of livestock disease control measures by farmers and can differ by region, which would have implications for disease control nationally. Methods We investigated altruism, trust, psychological proximity and the COM‐B behaviour change framework in a survey of 475 British cattle farmers
Naomi S. Prosser, Eamonn Ferguson, Jasmeet Kaler, Edward M. Hill, Michael J. Tildesley, Matt J. Keeling, Martin J. Green   +6 more
wiley   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Badgers as a potential source of bovine tuberculosis – first studies in Poland

Annals of Agricultural and Environmental Medicine, 2018
Since 2009, Poland has been recognized as a country officially free of bovine tuberculosis (BTB). However, new outbreaks are each year quoted. In many countries it has been shown that badgers ( Meles meles ) are a vector of Mycobacterium bovis/caprae (
Marek Lipiec, Krzysztof Nowakowski, Łukasz Radulski, Wojciech Iwaniak, Agnieszka Ważna   +4 more
doaj   +1 more source

Scoping review to assess online guidance about poultry farm biosecurity for farmers in the UK

Veterinary Record, EarlyView.
Abstract Background Biosecurity is the primary defence against diseases such as avian influenza (AI) for poultry farms. This research reviews online resources to assess the availability and topics shaping biosecurity advice for poultry farmers. Methods A rapid scoping review examined biosecurity guidelines available to UK poultry farmers on 10 websites
Eve Houghton, Ivo Syndicus, Paniz Hosseini, Timothy Borthwick, James L. N. Wood, Pablo Alarcon   +5 more
wiley   +1 more source

Bovine Tuberculosis in a Free Ranging Red Fox (Vulpes vulpes) from Doñana National Park (Spain) [PDF]

, 2005
During 1997 and 1998, a survey of Iberian carnivores was conducted to study the epidemiology of bovine tuberculosis in the Doñana National Park and surrounding areas in southwestern Spain.
Calzada, Javier, Cubero, María José, Gónzalez-Candela, M., León-Vizcaíno, Luis, Martín-Atance, Pablo, Palomares, Francisco, Revilla, Eloy   +6 more
core   +1 more source

Experimental assessment of large mammal population estimates from airborne thermal videography

Wildlife Biology, EarlyView.
Wildlife resource management requires reliable, fast, and affordable methods of surveying wildlife populations to develop and adaptively adjust policies. Thermal video from drones can yield high rates of detection over large areas with relative speed and safety.
Julia S. McElhinny, Gregory D. Larsen, Maxwell Messinger, Chad H. Newbolt, Andrew Whitworth, Stephen S. Ditchkoff, Miles R. Silman, Jared T. Beaver   +7 more
wiley   +1 more source

Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]

, 2018
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I, Köster, Stefan, Mehra, Alka, Mittal, Ekansh, Philips, Jennifer A, Skowyra, Michael L, Tinaztepe, Emir, Uwase, Grace   +7 more
core   +2 more sources