Results 61 to 70 of about 540,640 (234)

Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones

Austral Journal of Veterinary Sciences, 2018
There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis
Sinasi Askar, Tunay Kontas Askar, Murat Guzel   +2 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Inside Mycobacterium bovis SB0120 spoligotype circulating in Italy: analysis of the most frequent genotypes by whole genome sequencing

Frontiers in Microbiology
Bovine tuberculosis (bTB) is a chronic inflammatory disease primarily caused by Mycobacterium bovis. The infection affects domestic animals and wildlife, posing a zoonotic risk to humans.
Erika Scaltriti, Karaman Iyad, Maria Beatrice Boniotti, Ilaria Menozzi, Luca Bolzoni, Dorotea Ippolito, Flavia Pruiti Ciarello, Daniela Loda, Mario D’Incau, Mariagrazia Zanoni, Vincenzo Di Marco Lo Presti, Piera Mazzone, Stefano Gavaudan, Maria Lodovica Pacciarini   +13 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis [PDF]

, 2012
peer-reviewedBackground Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first cell types to encounter M.
Karsten Hokamp (42210), Magee, David A, Conlon, Kevin M., Park Stephen D. E., Gordon, Stephen V, Karsten Hokamp, David J. Lynn (107188), Conlon Kevin M., Lynn, David J, Taraktsoglou, Maria, Nicolas C Nalpas, Stephen D. E. Park (183071), Stephen V Gordon, Stephen V. Gordon (108974), MacHugh David E., Gordon Stephen V., Eamonn Gormley (84870), Nalpas Nicolas C., Nicolas C. Nalpas (183064), David A. Magee (183048), Killick, Kate E, John A Browne, MacHugh, David E, Nalpas, Nicolas C., Kate E Killick, David E MacHugh, Gormley, Eamonn, Lynn David J., David E. MacHugh (183089), Park, Stephen D. E., Hokamp, Karsten, David J Lynn, Maria Taraktsoglou (183055), Browne John A., Killick Kate E., Kevin M Conlon, Kevin M. Conlon (183076), Eamonn Gormley, Gormley Eamonn, David A Magee, Taraktsoglou Maria, Kate E. Killick (183061), Hokamp Karsten, Magee David A., Browne, John A, Stephen D E Park, Maria Taraktsoglou, John A. Browne (183068)   +47 more
core   +2 more sources

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Endemic cattle diseases : comparative epidemiology and governance [PDF]

, 2011
Cattle are infected by a community of endemic pathogens with different epidemiological properties which invoke different managerial and governmental responses. We present characteristics of pathogens that influence their ability to persist in the UK, and
McEldowney, John F., Matt Keeling, Carslake, David, Jonathan Cave, Graham F. Medley, Green, Laura E.; id_orcid, Keeling, Matt, Greaves, Justin, Medley, Graham F., David Carslake, Keeling, Matthew James, Laura E. Green, Cave, Jonathan, Weldegebriel, Habtu, Medley, Graham, Justin Greaves, McEldowney, John, Weldegebriel, Habtu Tadesse, Grant, Wyn, Green, Laura E., Habtu Weldegebriel, Cave, Jonathan A. K., John McEldowney, Wyn Grant   +23 more
core   +1 more source

Increased Plasma Microbial tDR‐1 in At‐Risk Individuals Is Associated With Decreased Conversion to Clinical Rheumatoid Arthritis and Reduces an In Vitro Macrophage Type 1 Interferon Response

Arthritis &Rheumatology, EarlyView.
Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane, Tulsi K. Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L. Feser, Jill M. Norris, M. Kristen Demoruelle, LauraKay Moss, Kevin D. Deane, V. Michael Holers, Michelle J. Ormseth   +11 more
wiley   +1 more source

Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology?

Onderstepoort Journal of Veterinary Research
Paratuberculosis (Johne’s disease) has devastating outcomes on ruminant health and impacts on national and international trade. The current work assessed the diagnostic value of the VersaTREK automated liquid culture system in isolating Mycobacterium ...
Motlatso T. Hlokwe, Nomawethu S. Masina, Boitumelo Letsoko, Sewellyn C. Davey, Anita L. Michel   +4 more
doaj   +1 more source

La tuberculose humaine et animale au Tchad : contribution à la mise en évidence et caractérisation des agents causaux et leur implication en santé publique [PDF]

, 2004
Chad is a high-incidence country for clinical tuberculosis. Within the last decade, the annual incidence rate increased from 120 human tuberculosis cases per 100’000 people to 370/100’000 in 2004.
Diguimbaye, Colette
core   +1 more source