Results 41 to 50 of about 578,194 (243)

Endemic cattle diseases : comparative epidemiology and governance [PDF]

, 2011
Cattle are infected by a community of endemic pathogens with different epidemiological properties which invoke different managerial and governmental responses. We present characteristics of pathogens that influence their ability to persist in the UK, and
McEldowney, John F., Matt Keeling, Carslake, David, Jonathan Cave, Graham F. Medley, Green, Laura E.; id_orcid, Keeling, Matt, Greaves, Justin, Medley, Graham F., David Carslake, Keeling, Matthew James, Laura E. Green, Cave, Jonathan, Weldegebriel, Habtu, Medley, Graham, Justin Greaves, McEldowney, John, Weldegebriel, Habtu Tadesse, Grant, Wyn, Green, Laura E., Habtu Weldegebriel, Cave, Jonathan A. K., John McEldowney, Wyn Grant   +23 more
core   +1 more source

Human and bovine tuberculosis knowledge, attitude and practice (KAP) among cattle owners in Ethiopia

Heliyon, 2021
Tuberculosis (TB) is a re-emerging disease occurring worldwide, resulting in multi-billion-dollar loss and human death annually. The situation is worse in developing countries like Ethiopia, where lower knowledge, attitude, and practice (KAP) of the ...
Amare Bihon, Solomon Zinabu, Yimer Muktar, Ayalew Assefa   +3 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Prevalence and Direct Economic Losses from Bovine Tuberculosis in Makurdi, Nigeria

Veterinary Medicine International, 2014
A retrospective study was conducted to investigate the prevalence of bovine tuberculosis and direct economic losses (DEL) from tuberculosis in cattle slaughtered in Makurdi abattoirs from 2008 to 2012, using abattoir records obtained from the Ministry of
E. F. Ejeh, M. A. Raji, M. Bello, F. A. Lawan, M. I. Francis, A. C. Kudi, S. I. B. Cadmus   +6 more
doaj   +1 more source

Introduction and Application of the Interferon-γ Assay in the National Bovine Tuberculosis Control Program in South Korea

Frontiers in Veterinary Science, 2020
Bovine tuberculosis is a chronic disease impacting both public health and the livestock industry. The interferon (IFN)-γ assay has been introduced as an ancillary test for diagnosing bovine tuberculosis to overcome limitations of the skin test.
Yun-Ho Jang, Tae-woon Kim, Min Kyu Jeong, Yoon Jeong Seo, Soyoon Ryoo, Chan Ho Park, Sin seok Kang, Young Ju Lee, Soon-Seek Yoon, Jae Myung Kim   +9 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

M. caprae in northern Italy: a comprehensive analysis through whole-genome sequencing on the genetic variability in bovine herds

Veterinary Research
Mycobacterium (M.) bovis and M. caprae are the causative agents of bovine tuberculosis (bTB), which is still a concern due to its health implications and economic impact. Although M. caprae is less prevalent than M. bovis among bovine tuberculosis cases,
Cristina Bertasio, Valentina Carta, Giovanni Parisio, Mariagrazia Zanoni, Marco Tamba, Laura Mazzera, Erika Scaltriti, Maria Lodovica Pacciarini, Giovanni Loris Alborali, Daniel Polzer, Annette Nigsch, Romana Steinparzer, Maria Beatrice Boniotti   +12 more
doaj   +1 more source

BOVINE AND HUMAN TUBERCULOSIS. [PDF]

JAMA: The Journal of the American Medical Association, 1904
In the last two reports presented by this committee considerable space was devoted to the subject of tuberculosis, and particularly to that phase of it which relates to the transmission of the disease from animals to man. It was shown from a review of the facts obtained by different methods of inquiry that the clinical evidence, the evidence of ...
openaire   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle [PDF]

, 2006
Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
C. J. Howard, Howard, C J, Hope, J C; id_orcid, P. Sopp, J. C. Hope, Sopp, P   +5 more
core   +1 more source