Results 31 to 40 of about 45,570 (177)

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

M. caprae in northern Italy: a comprehensive analysis through whole-genome sequencing on the genetic variability in bovine herds

Veterinary Research
Mycobacterium (M.) bovis and M. caprae are the causative agents of bovine tuberculosis (bTB), which is still a concern due to its health implications and economic impact. Although M. caprae is less prevalent than M. bovis among bovine tuberculosis cases,
Cristina Bertasio, Valentina Carta, Giovanni Parisio, Mariagrazia Zanoni, Marco Tamba, Laura Mazzera, Erika Scaltriti, Maria Lodovica Pacciarini, Giovanni Loris Alborali, Daniel Polzer, Annette Nigsch, Romana Steinparzer, Maria Beatrice Boniotti   +12 more
doaj   +1 more source

Prevalence and Direct Economic Losses from Bovine Tuberculosis in Makurdi, Nigeria

Veterinary Medicine International, 2014
A retrospective study was conducted to investigate the prevalence of bovine tuberculosis and direct economic losses (DEL) from tuberculosis in cattle slaughtered in Makurdi abattoirs from 2008 to 2012, using abattoir records obtained from the Ministry of
E. F. Ejeh, M. A. Raji, M. Bello, F. A. Lawan, M. I. Francis, A. C. Kudi, S. I. B. Cadmus   +6 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Matrixlysis, an improved sample preparation method for recovery of Mycobacteria from animal tissue material. [PDF]

PLoS ONE, 2017
Mycobacterium caprae, a member of the Mycobacterium tuberculosis complex, is the main causative agent of bovine tuberculosis in alpine regions. Bacterial culture is the gold standard in bovine tuberculosis diagnostic but takes up to twelve weeks.
Christoph Leth, Ashok Varadharajan, Patrick Mester, Marlis Fischaleck, Peter Rossmanith, Friedrich Schmoll, Maria Fink   +6 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Molecular Characterization of Mycobacterium tuberculosis Isolates From West of Iran Using Mycobacterial Interspersed Repetitive Unit‐Variable Number Tandem Repeats: A Cross‐Sectional Study

Health Science Reports
Background and Aims Tuberculosis (TB) remains a major global health problem and poses significant challenges for diagnosis and treatment. The World Health Organization (WHO) recommends the use of molecular methods for the diagnosis and genotyping of ...
Mohammad Yazdanmanesh, Keyvan Tadayon, Hossein Kazemian, Nilufar Sadouqi, Nader Mosavari   +4 more
doaj   +1 more source

Molecular Characterisation of Mycobacterium bovis Isolates from Cattle Slaughtered in Adamawa and Gombe States, North-Eastern Nigeria

Current Issues in Molecular Biology, 2023
Bovine tuberculosis is endemic in Nigeria with control measures as provided by the laws of the country being minimally enforced mostly at the abattoirs only. This study focused on bovine tuberculosis in Adamawa and Gombe States. Tuberculosis lesions were
Sadiq Mohammed Damina, David Atomanyi Barnes, Bitrus Inuwa, Gulak Hussaini Ularamu, Mohammed Bello, Olu Solomon Okaiyeto, Ayuba Caleb Kudi, Jeewan Thapa, Chie Nakajima, Yasuhiko Suzuki   +9 more
doaj   +1 more source

Increased plasma microbial tDR‐1 in at‐risk individuals is associated with decreased conversion to clinical rheumatoid arthritis and reduces an in vitro macrophage type 1 interferon response

Arthritis &Rheumatology, Accepted Article.
Background Microbial small RNAs (sRNAs) can regulate human genes. Higher plasma concentrations of microbial tRNA‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anti‐cyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (ARI)
Anastasiia Phothisane, Tulsi K Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L Feser, Jill M Norris, M Kristen Demoruelle, LauraKay Moss, Kevin D Deane, V Michael Holers, Michelle J Ormseth   +11 more
wiley   +1 more source

Bovine tuberculosis: a retrospective study at Jos abattoir, Plateau State, Nigeria

The Pan African Medical Journal, 2016
INTRODUCTION: Nigeria has the thirteenth highest burden of human tuberculosis. The current increasing incidence of tuberculosis in humans, particularly in immune-compromised persons, has given interest in the zoonotic importance of Mycobacterium bovis in
Lilian Akudo Okeke, Olufunmilayo Fawole, Maryam Muhammad, Ikenna Osemeka Okeke, Patrick Nguku, Peter Wasswa, David Dairo, Simeon Cadmus   +7 more
doaj   +1 more source