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Immune evasion strategies of bovine viral diarrhea virus [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
Bovine viral diarrhea virus (BVDV) is a significant pathogen that causes great economic losses in the global livestock industry. During the long-term interactions between BVDV and its hosts, the virus has evolved multiple strategies to evade the host’s innate immunity and adaptive immunity, thereby promoting viral survival and replication.
Feng Pang, Qinqin Long, Min Wei
europepmc   +5 more sources

Isolation of Bovine Viral Diarrhea Virus from an Alpaca [PDF]

Journal of Veterinary Diagnostic Investigation, 2002
A frozen, stillborn alpaca ( Lama pacos) was submitted to the Minnesota Veterinary Diagnostic Laboratory for diagnostic purposes. No gross or histopathologic changes of any significance were seen. A pool of lung, liver, and brain tissues was positive for bovine viral diarrhea virus (BVDV) by reverse transcription–polymerase chain reaction.
Sagar M. Goyal, Mostafa Bouljihad, Sigrun Haugerud, Julia F. Ridpath   +3 more
openalex   +4 more sources

The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.) [PDF]

, 2014
The N-terminal protease of pestiviruses, N(pro) is a unique viral protein, both because it is a distinct autoprotease that cleaves itself from the following polyprotein chain, and also because it binds and inactivates IRF3, a central regulator of ...
C Achmüller, C Castanier, CA Benedict, D Hoepfner, E Dixit, E Peterhans, F Hou, HW Platta, Irina Mohorianu, JC Martinou, JE Vince, Karen L. Mossman, KE Taylor, KV Mohan, Matthew Jefferson, Matthew Whelband, MJ Killip, MR Szymanski, N Ruggli, N Zemirli, O Bauhofer, PB Lazarow, Penny P. Powell, R Higgs, RB Seth, RE Lloyd, S Chattopadhyay, S Paz, S Sharma, SA La Rocca, SM Belgnaoui, SW Tait, T Wolff, TJ Ettema, V Doceul, V Moennig, Y Li   +36 more
core   +16 more sources

Detection of Bovine Viral Diarrhea Virus in the Ovaries of Cattle Acutely Infected with Bovine Viral Diarrhea Virus [PDF]

Journal of Veterinary Diagnostic Investigation, 1998
Bovine viral diarrhea virus (BVDV) is recognized worldwide as a major cause of economic loss in cattle. Infection with BVDV can result in several clinical outcomes. However, the reproductive consequences may be the most important. Infertility, early embryonic death, abortion, and congenital anomalies have all been reported following acute infection ...
Kenny V. Brock, Daniel L. Grooms, L. A. Ward   +2 more
openaire   +3 more sources

Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea [PDF]

, 2013
Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of VP6-specific llama-derived single domain nanoantibodies (VHH nanoAbs) against different RVA strains ...
Alvarado, Carmen, Bok, Karin, Bok, Marina, Chattha, Kuldeep S., Escribano, José M., Fernández, Fernando, Garaicoechea, Lorena Laura, Gómez Sebastián, Silvia, Lasa, Rodrigo, Nuñez, Carmen, Parreño, Gladys Viviana, Saif, Linda J., Vega, Celina Guadalupe, Vlasova, Anastasia N., Wigdorovitz, Andrés   +14 more
core   +7 more sources

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]

, 2015
Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A, Anstaett, O L, Brownlie, J, Cheng, Z R, Fouladi-Nashta, A A, Oguejiofor, C F, Wathes, D C   +6 more
core   +1 more source

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo [PDF]

, 2002
In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals.
Brackenbury, L.S, Carr, B V, Charleston, B, Fray, M D, Hope, Jayne, Howard, CJ, Morrison, Ivan   +6 more
core   +2 more sources

Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]

, 2017
Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K, Gershwin, Laurel J, Grupioni, Natalia V, Kim, JaeWoo, Neibergs, Holly L, Regitano, Luciana CA, Schnabel, Robert D, Seabury, Christopher M, Taylor, Jeremy F, Tizioto, Polyana C, Toaff-Rosenstein, Rachel, Van Eenennaam, Alison L   +11 more
core   +3 more sources

Characterization of bovine viral diarrhea virus RNA [PDF]

Journal of Virology, 1975
RNA extracted from isopycnically banded [3-H]uridine-labeled bovine viral diarrhea virus with sodium dodecyl sulfate was resolved into one major and two minor components by both sedimentation analysis and electrophoresis in polyacrylamide gels. The major RNA component was estimated to have a 38S sedimentation coefficient.
R Pritchett, J S Manning, Y C Zee
openaire   +3 more sources

Economic evaluation of the eradication program for bovine viral diarrhea in the Swiss dairy sector [PDF]

, 2017
The aim of this study was to conduct an economic evaluation of the BVD eradication program in the Swiss dairy sector. The situation before the start of the program (herd-level prevalence: 20%) served as a baseline scenario.
Häsler, B, Magouras, I, Meylan, M, Schüpbach-Regula, G, Thomann, B, Tschopp, A   +5 more
core   +1 more source