Results 81 to 90 of about 1,649,716 (257)

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

open access: yesAdvanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu   +12 more
wiley   +1 more source

Therapeutic efficacy of bovine ultra-long CDR H3 antibody against BVDV in challenged BALB/c mouse model

open access: yesFrontiers in Immunology
Bovine Viral Diarrhea Virus (BVDV), the etiologic agent of bovine viral diarrhea, poses substantial economic threats to the cattle industry worldwide. While vaccination represents the cornerstone of preventive strategies, relying primarily on inactivated
Gege Rile   +9 more
doaj   +1 more source

Efficacy of a non-adjuvanted, modified-live virus vaccine in calves with maternal antibodies against a virulent bovine viral diarrhea virus type 2a challenge seven months following vaccination

open access: yes, 2010
In the presence of maternal antibodies, 26 calves three days of age were either vaccinated (n=15) with a single dose of a non-adjuvanted, pentavalent, modified-live vaccine containing bovine herpes virus-1, bovine respiratory syncytial virus, bovine ...
Bolton, Michael W.   +5 more
core   +1 more source

Complete Genome Sequence of a Bovine Viral Diarrhea Virus Subgenotype 1e Strain Isolated in Switzerland [PDF]

open access: yes, 2015
We sequenced the complete genome of the bovine viral diarrhea virus (BVDV) strain Carlito. It belongs to the subgenotype 1e that is described in Europe only and represents the second most prevalent subgenotype in Switzerland.
Schweizer, Matthias   +2 more
core   +2 more sources

Establishment and characterization of mouse lymph node fibrosis models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu   +8 more
wiley   +1 more source

Effect of bovine viral diarrhea virus in the feedlot

open access: yesVeterinary Clinics of North America: Food Animal Practice, 2004
It could be argued that bovine viral diarrhea virus (BVDV) is one of the most economically significant infectious pathogens of feedlot cattle. Although the direct economic losses caused by this virus have not been well quantified, the role it plays as an immunosuppressive agent and as a potentiator for other diseases, most notably bovine respiratory ...
openaire   +2 more sources

Editorial: Pestivirus: Epidemiology, evolution, biology and clinical features

open access: yesFrontiers in Veterinary Science, 2022
Fernando Viçosa Bauermann   +3 more
doaj   +1 more source

Diagnosis of A Novel Variant of Bovine Viral Diarrhea Virus Infection in a Bull

open access: yes, 2000
Bovine viral diarrhea virus BVDV is economically devastating to the beef and dairy industries in most parts of the world, and diagnosing variant strains of BVDV can challenge the practitioner.
Gnad, D.   +3 more
core   +1 more source

Assessing the Epidemiologic Impact of Vaccination for Bovine Viral Diarrhea Virus

open access: yes, 2008
Currently, to validate efficacy of BVDV vaccines, clinical trials commonly involve challenge of vaccinates with a single intranasal inoculation of a BVDV field strain.
Marley, M. S. D.   +5 more
core   +1 more source

ОЧИСТКА И КОНЦЕНТРИРОВАНИЕ ВИРУСА ДИАРЕИ-БОЛЕЗНИ СЛИЗИСТЫХ ОБОЛОЧЕК КРУПНОГО РОГАТОГО СКОТА

open access: yesВетеринарная патология, 2007
Experimental data on purification and concentration of NADL strain of bovine viral diarrhea-mucosal disease virus are presented in the paper.

doaj  

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