Results 61 to 70 of about 5,981,486 (219)

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, Volume 13, Issue 54, 28 September 2026.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

A Field Study of Calves Persistently Infected with the Bovine Viral Diarrhea Virus, Type I and II, in a Pennsylvania Dairy Herd

, 1995
An outbreak of bovine viral diarrhea (BVD) virus. infection with severe clinical manifestations occurred in seven herds of cattle primarily in Northwest PA during the spring of 1994.
Stoffregen, W., Hattel, A. L., Crawford, W. H., Smith, A., Castro, A. E., Drake, T. R.   +5 more
core   +1 more source

Isolation and Genetic Analysis of Bovine Viral Diarrhea Virus from Infected Cattle in Indiana

Veterinary Medicine International, 2011
Species and biotype distribution was determined in 44 bovine viral diarrhea virus- (BVDV-) positive samples submitted to the Animal Disease Diagnostic Laboratory (ADDL) in Indiana during 2006–2008.
Roman M. Pogranichniy, Megan E. Schnur, Eran A. Raizman, Duane A. Murphy, Maria Negron, H. Leon Thacker   +5 more
doaj   +1 more source

Demonstration of Vd-Virus by the Fluorescent Antibody Technique in Tissues of Cattle Affected with Bovine Viral Diarrhea (Mucosal Disease) [PDF]

Acta Veterinaria Scandinavica, 1970
An account is given of immunohistological studies performed on tissue specimens from 59 cattle affected with BVD-MD. The animals had either died or been killed in an advanced state of the disease. From 47 of these animals VD-virus was demonstrated in primary calf kidney cultures inoculated with suspensions of at least one of the following tissues ...
openaire   +2 more sources

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Bovine Viral Diarrhea - Mucosal Disease [PDF]

, 1984
Bovine Viral Diarrhea Mucosal Disease merupakan suatu penyakit komplek yang disebabkan oleh virus. Penyakit ini dapat menyerang- golongan ruminansia terutama sapi. · Pertama kali kejadian penyakit ini dilaporkan oleh Olafson · pada tahun 1946 di New York.
Wildan Arief Noortjahjo, -
core   +1 more source

Evaluation of effectiveness of solvent-detergent viral in activation in the manufacture of intravenous human immunoglobulin G in a model of virus diarrhea — mucosal disease of cattle

RUDN Journal of Medicine, 2013
In model experiments using in vitro virus diarrhea — mucosal disease in cattle (bovine VD-MDC) studied the effectiveness of solvent-detergent (SD) virus inactivation used in the production of intravenous human immunoglobulin G (IgG). Optimized conditions
A V Kaz’yanin, N V Zubkova, I V Krasilnikov, A K Lobastova, V V Anastasiev, A M Nikolaeva, T I Glotova, O V Kungurtseva, A G Glotov   +8 more
doaj  

A search for RNA insertions and NS3 gene duplication in the genome of cytopathic isolates of bovine viral diarrhea virus

Brazilian Journal of Medical and Biological Research, 2006
Calves born persistently infected with non-cytopathic bovine viral diarrhea virus (ncpBVDV) frequently develop a fatal gastroenteric illness called mucosal disease.
V.L. Quadros, S.V. Mayer, F.S.F. Vogel, R. Weiblen, M.C.S. Brum, S. Arenhart, E.F. Flores   +6 more
doaj   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, Volume 3, Issue 3, September 2026.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source