Results 11 to 20 of about 12,276 (186)

Bio-oil production from ripe pawpaw seeds and its optimal output: Box-Behnken Design and Machine Learning approach

open access: yesScientific African, 2023
The purpose of this study is to use ripe pawpaw seeds for a rapid Soxhlet extractor process with n-hexane to increase the yield of the bio-oil and to make the bio-oil produced a beneficial addition to the field of bio-oil production parameter ...
Sunday Chukwuka Iweka   +3 more
doaj   +1 more source

Preparation, Characterization, and Evaluation of Breviscapine Nanosuspension and Its Freeze-Dried Powder

open access: yesPharmaceutics, 2022
As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological half-life and rapid removal from plasma.
Ting Zhang   +5 more
doaj   +1 more source

NANOSTRUCTURED LIPOSOMES FOR NOSE TO BRAIN DELIVERY OF CARMUSTINE: IN VIVO EVALUATION [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2022
Nano sized particles are promising mediators for the administration of active compounds in the nasal and cerebral systems. However, the ability to achieve relevant therapeutic concentrations of exogenous molecules in the body is dependent mainly on the ...
K.B. Sekhar, M. Alagusundaram, G. Vani
doaj   +1 more source

Penerapan Desain Eksperimen Plackett-Burman dan Box-Behnken pada Analisis Voltametri Pulsa Diferensial untuk Penentuan Kadar Senyawa Kompleks Gd-DTPA

open access: yesAlchemy, 2020
Gadolinium merupakan salah satu golongan unsur tanah jarang yang menarik karena memiliki sifat paramagnetik yang tinggi. Pengkhelatan gadolinium dengan ligan dietilentriaminpentaasetat (DTPA) menghasilkan senyawa yang berguna dalam bidang kesehatan ...
Santhy Wyantuti   +3 more
doaj   +1 more source

A comparison of two hybrid optimization techniques: the Taguchi-BBD-firefly and the Taguchi-regression-firefly methods on the IS 2062-E250 steel plates boring problem

open access: yesJournal of Engineering and Applied Science, 2023
The expanding proliferation of components for engineering applications requires greater optimisation of parameters, which consequently increases the need for more efficient boring practices.
Ebun Fasina   +3 more
doaj   +1 more source

Honokiol-Loaded Nanoemulsion for Glioblastoma Treatment: Statistical Optimization, Physicochemical Characterization, and an In Vitro Toxicity Assay

open access: yesPharmaceutics, 2023
Background: Glioblastoma (GBM) is an extremely invasive and heterogenous malignant brain tumor. Despite advances in current anticancer therapy, treatment options for glioblastoma remain limited, and tumor recurrence is inevitable.
Aleksandra Gostyńska   +6 more
doaj   +1 more source

The application of Box-Behnken-Design in the optimization of HPLC separation of fluoroquinolones [PDF]

open access: yesScientific Reports, 2019
AbstractBox-Behnken Design is a useful tool for the optimization of the chromatographic analysis. The goal of this study was to select the most significant factors that influenced the following parameters of the chromatographic separation: retention time, relative retention time, symmetry of the peaks, tailing factor, a number of theoretical plates ...
Andrzej Czyrski, Justyna Sznura
openaire   +2 more sources

Study of alcoholic fermentation of an aqueous extract of butiá palm (Butia eriospatha (Martius) Beccari) pulp: Optimization by response surface methodology

open access: yesSemina: Ciências Exatas e Tecnológicas, 2015
The fermentation conditions were established and an incomplete Box-Behnken factorial design was applied. The independent variables used were yeast extract, yeast and NH4H2PO4, and the alcohol yield obtained was optimized.
Caroline de Souza Cardoso   +6 more
doaj   +1 more source

Box–Behnken Design of Experiments of Polycaprolactone Nanoparticles Loaded with Irinotecan Hydrochloride

open access: yesPharmaceutics, 2023
Background: The Box–Behnken design of experiments (BBD) is a statistical modelling technique that allows the determination of the significant factors in developing nanoparticles (NPs) using a limited number of runs.
Basant Salah Mahmoud   +1 more
doaj   +1 more source

Statistical modeling and optimization of ultrasound-assisted biodiesel production using various experimental designs

open access: yesZaštita Materijala, 2019
The present study compares the performances of the regression models developed by the response surface methodology combined with the full factorial, Box-Behnken or face central composite designs applied for the ultrasound-assisted KOH-catalyzed ...
Vlada B. Veljković   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy