USE OF BOX–BEHNKEN DESIGN FOR OPTIMIZATION OF COMPOUNDED MEDICATION: ACYCLOVIR CAPSULES REPORT
Campus compounding pharmacies play an important role in public health. Herpes simplex is one of the most common viral diseases in humans, which generates a great demand for acyclovir capsules in compounding pharmacy. It is well known that the formulation'
Suelen da Silva Reis +7 more
doaj +5 more sources
Optimization of paclitaxel loaded poly (ε-caprolactone) nanoparticles using Box Behnken design
Optimization is a critical process in the development of nanoparticles to apprehend the formulation variables and quality attributes. The purpose of this study was to evaluate the influence of formulation variables viz., drug/polymer ratio (A ...
Nandhakumar Sathyamoorthy +3 more
doaj +1 more source
Evaluating Percentage Rotatability For The Small Box – Behnken Design
Rotatability property for the Small Box-Behnken design is discussed in this paper. This paper aimed at applying a measure of obtaining percentage rotatability on the Small Box-Behnken designs to determine if the Small Box-behnken designs are rotatable or not and investigated the extent of rotatability in terms of percentage.
Lawrence Chizoba Kiwu +4 more
openaire +2 more sources
Chemical extraction and optimization of intracellular β-galactosidase production from the bacterium Arthrobacter oxydans using Box-Behnken design of response surface methodology [PDF]
Present study demonstrated the isolation of most promising β-galactosidase producing bacterial strain SB from soil. Morphological, biochemical, and 16s rRNA sequence analysis identified the bacterial strain as Arthrobacter oxydans.
Banerjee, G. +4 more
core +1 more source
A virtual experiment conducted using the ICP-MS TuneSim software served as the basis for studies that compared the applicability of the central composite design with the Box–Behnken design in analytical chemistry applications.
Agnieszka Królicka, Anna Szczurkowska
doaj +1 more source
Optimization of conventional spinning process parameters by means of numerical simulation and statistical analysis [PDF]
Research in sheet metal spinning has increased due to a greater demand, especially in the transportation industries, for parts with very high strength-to-weight ratios with low cost.
Essa, K, Hartley, P
core +1 more source
Optimizing a sustainable ultrasound assisted extraction method for the recovery of polyphenols from lemon by-products:comparison with hot water and organic solvent extractions [PDF]
Response surface methodology (RSM) based on a three-factor and three-level Box–Behnken design was employed for optimizing the aqueous ultrasound-assisted extraction (AUAE) conditions, including extraction time (35–45 min), extraction temperature (45–55 ...
Bowyer, Michael C. +6 more
core +2 more sources
Optimization of a Centrifugal Compressor Using the Design of Experiment Technique [PDF]
Centrifugal compressor performance is affected by many parameters, optimization of which can lead to superior designs. Recognizing the most important parameters affecting performance helps to reduce the optimization process cost.
Aungier, Mason, Mojaddam
core +1 more source
Silver nanoparticles in the medical field are used as additives in vaccines, anti-diabetic agents, wound and bone healing, biosensors and anticancer therapy in medical applications.
Qinta Laily Nurjana +3 more
doaj +1 more source
Rheological and Mechanical Analyses of Felbinac Cataplasms by Using Box–Behnken Design
Felbinac, an active pharmaceutical ingredient (API) used clinically for the treatment of osteoarthritis, has poor solubility. Felbinac cataplasm product design was investigated using rheological and mechanical analyses.
Jie Yang +3 more
doaj +1 more source

