Results 41 to 50 of about 33,090 (202)

Quality-by-design based fabrication of febuxostat-loaded nanoemulsion: Statistical optimization, characterizations, permeability, and bioavailability studies

Heliyon, 2023
The present work deals with QbD-based development of FEB-loaded nanoemulsion (FEB-NE) in order to enhance bioavailability and permeability. In the beginning, the risk assessment was performed on different experimental variables using the Ishikawa diagram
Vishal C. Gurumukhi, Vivek P. Sonawane, Ganesh G. Tapadiya, Sanjaykumar B. Bari, Sanjay J. Surana, Shailesh S. Chalikwar   +5 more
doaj   +1 more source

KH2PO4 improves cellulase production of Irpex lacteus and Pycnoporus sanguineus [PDF]

, 2018
The optimization of cellulase production by Irpex lacteus and Pycnoporus sanguineus was investigated. Fractional factorial design was conducted to determine significant variables and interactions.
Alonso Paiva, Iván Mathias, Castrillo, María Lorena, Rodríguez, María Daniela, Villalba, Laura Lidia, Zapata, Pedro Dario   +4 more
core   +1 more source

Effect of process parameters and optimization of CO2 laser cutting of ultra high performance polyethylene [PDF]

, 2010
The aim of this work is to relate the cutting edge quality parameters (responses) namely: upper kerf, lower kerf, ratio of the upper kerf to lower kerf and cut edge roughness to the process parameters considered in this research and to find out the ...
A.G. Olabi, Caiazzo, Choudhury, Davim, Davim, H.A. Eltawahni, K.Y. Benyounis, Khuri, Kurt, Montgomery, Naceur, Olabi, Powell, Shuaeib   +13 more
core   +1 more source

Optimization of bioethanol production from simultaneous saccharification and fermentation of pineapple peels using Saccharomyces cerevisiae

Journal of Applied Sciences and Environmental Management, 2018
In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design (BBD) and response surface methodology
O Oiwoh, B.V. Ayodele, N.A. Amenaghawon, C.O. Okieimen   +3 more
doaj   +3 more sources

Optimization of the experimental parameters of fluticasone propionate microparticles for pulmonary delivery using a box behenken design

Journal of Pharmacy and Bioallied Sciences, 2012
The objective of this study was to examine extensively the influences of formulation and process variables on the microparticles. The microparticles were generated by the spray-drying technique using polymer chitosan, mannitol along with L-leucine.
P V Patel, T G Soni, V T Thakkar, T R Gandhi   +3 more
doaj   +1 more source

Optimization Studies on Imatinib Mesylate Loaded Nanoliposomes Using Box-Behnken Design

Nano Biomedicine and Engineering, 2022
Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed to investigate the effects of critical variables on nanoliposomes characteristics.
Mandeep Dahiya, Rajendra Awasthi, Gaurav Gupta, Sachin Kumar Singh, Monica Gulati, Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Parteek Prasher, Krishnan Anand, Dinesh Kumar Chellappan, Kamal Dua, Harish Dureja   +12 more
doaj   +1 more source

Reliability approach for safe designing on a locking system [PDF]

, 2010
The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe, DAU, Frédéric, GUILLAUMAT, Laurent, MEALIER, Nicolas   +3 more
core   +3 more sources

Preparation of superhydrophobic nanocalcite crystals using Box–Behnken design

Arabian Journal of Chemistry, 2019
AbstractSuperhydrophobic nanocalcite crystals were prepared via an adjusted aqueous reaction of CaO, CO2 gas and sodium oleate. Box–Behnken design was used to optimize the preparation parameters such as CaO concentration, CO2 gas flow rate and surfactant concentration. The results revealed that the produced CaCO3 is indexed to the calcite phase.
Barhoum, Ahmed, M. El-Sheikh, Said, El-Sherbiny, Samya, A. Morsy, Fatma, Abdel-Hamid El-Midany, Ayman, Rahier, Hubert   +5 more
openaire   +2 more sources

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A., Fauzia, R. P., Gunawan, A. H., Mutalib, A.   +3 more
core  

Designing pulse laser surface modification of H13 steel using response surface method [PDF]

, 2011
This paper presents a design of experiment (DOE) for laser surface modification process of AISI H13 tool steel in achieving the maximum hardness and minimum surface roughness at a range of modified layer depth.
Aqida, S.N., Brabazon, Dermot, Naher, Sumsun   +2 more
core   +1 more source