Results 121 to 130 of about 159,946 (279)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Spartan Daily, November 1, 1983 [PDF]

open access: yes, 1983
Volume 81, Issue 45https://scholarworks.sjsu.edu/spartandaily/7094/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Effects of boxing exercise in people with Parkinson’s disease: a systematic review

open access: yesFrontiers in Aging Neuroscience
ObjectiveParkinson’s disease (PD) is a chronic neurodegenerative disorder characterized by progressive changes in both motor and non-motor symptoms. Boxing exercise can improve PD symptoms. This review aimed to determine the effects of boxing exercise on
Zhihai Wang   +11 more
doaj   +1 more source

Spartan Daily, September 8, 1986 [PDF]

open access: yes, 1986
Volume 87, Issue 7https://scholarworks.sjsu.edu/spartandaily/7464/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Black Boxes

open access: yes, 2008
We shall deal comprehensively with Black Boxes, the intention being that provably in ZFC we have a sequence of guesses of extra structure on small subsets, where the guesses are pairwise almost disjoint; by this we mean they have quite little interaction, and are far apart but together are dense.
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Essential visual skills required for boxing: A review

open access: yesAfrican Vision and Eye Health
Background: Boxing requires athletes to possess specific visual skills to effectively evaluate situations and react in a timely manner. Understanding these skills is crucial for the training and development of athletes.
S’bongile Mahlangu   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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