Results 71 to 80 of about 159,946 (279)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Spartan Daily, January 14, 1948 [PDF]
, 1946 Volume 36, Issue 61https://scholarworks.sjsu.edu/spartandaily/11021/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +3 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
, 2018 The crucial premise of the standard argument for two‐boxing in Newcomb's problem, a causal dominance principle, is false. We present some counterexamples. We then offer a metaethical explanation for why the counterexamples arise.
Spencer, Jack, Wells, Ian Thomas
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Journal of Parkinson’s Disease, 2019 Background: Persons with Parkinson’s disease (PD) benefit from continuous exercise through participation in community-based exercise programs. However, community programs often lack PD-specific knowledge needed to provide safe and adequately dosed ...
Josefa Domingos +8 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Les savoirs dans la salle de boxe thaï
Revue d'anthropologie des connaissances, 2014 Based on an ethnographic study through participant observation and interviews in a Thai boxing gym in a working-class banlieue, this article analyses the modalities of the transmission of Thai boxing and its social effects.
Akim Oualhaci
doaj +1 more source
Spartan Daily, December 11, 1942 [PDF]
, 1942 Volume 31, Issue 49https://scholarworks.sjsu.edu/spartandaily/3529/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source