Results 51 to 60 of about 12,167,877 (179)

E3 Ubiquitin Ligases: Structures, Biological Functions, Diseases, and Therapy

open access: yesMedComm, Volume 6, Issue 12, December 2025.
E3 ligases function as critical regulators of cellular protein degradation, and their dysregulation is a core pathogenic mechanism in a wide array of human diseases, including cancer, cardiovascular conditions, neurodegenerative disorders, and autoimmune diseases.
Haochen Wang   +6 more
wiley   +1 more source

New Hierarchical Phosphorylation Pathway of the Translational Repressor eIF4E-binding Protein 1 (4E-BP1) in Ischemia-Reperfusion Stress

open access: yes, 2010
Eukaryotic initiation factor (eIF) 4E-binding protein 1 (4E-BP1) is a translational repressor that is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G.
Salinas, Matilde   +9 more
core   +1 more source

Dyah Kunthi Talibrata Sebagai Representasi Profil Wanita Jawa Sejati

open access: yesMadaniyah: Terciptanya Insan Akademis Berkualitas & Berakhlak Mulia, 2016
Masyarakat Jawa di dalam cerita pewayangan memiliki seorang tokoh wanita yang patut diteladani yaitu bernama Dyah Ayu Kunthi. Perjalanan hidup Dyah Ayu Kunthi Talibrata sangat menyedihkan, akan tetapi dia mampu menunjukkan  harga  diri dan membuat  semua 
Hartini .
doaj  

Salahuddin Wahid and the Defence of Minority Rights in Contemporary Indonesia

open access: yesAl-Jami'ah: Journal of Islamic Studies, 2014
This paper discussed the role and authority of Salahuddin Wahid, a prominent muslim scholar, who actively promotes the minority rights in modern-day Indonesia.
Asfa Widiyanto
doaj   +1 more source

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

open access: yesMedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang   +10 more
wiley   +1 more source

Strategi Pembelajaran Anak Usia Dini Berbasis Multiple Intelligence

open access: yesMadaniyah: Terciptanya Insan Akademis Berkualitas & Berakhlak Mulia, 2017
Gardner explains that intelligence is some of the abilities that a person possesses, which will not all be equal to the abilities others have, because they are of many types, Gardner calls them multiple intelligences. The development of learning strategy
Yuliana Habibi   +3 more
doaj  

The Ideals and Interests in Intellectuals’ Political Deliberations

open access: yesAmerican Journal of Islam and Society, 2023
The academic literature equates the Arab Spring politics of Egypt’s two highest official religious figures – the Shaykh al-Azhar Ahmad al-Tayyib and Grand Mufti Ali Gomaa—as “anti-revolutionary.” This article argues that al-Tayyib and Gomaa’s politics ...
Muhammad Amasha
doaj   +1 more source

Short‐Term Severe Energy Restriction Promotes Molecular Health and Reverses Aging Signatures in Adults With Prediabetes in the PREVIEW Study

open access: yesAging Cell, Volume 24, Issue 8, August 2025.
Severe short‐term energy restriction in adults with prediabetes led to a significant reduction in circulating proteins linked to inflammation, senescence, and protein turnover. These changes, partly mediated by extracellular vesicles, suggest systemic dietary‐induced benefits beyond glycemic control, including improved aging biomarkers.
Maria Lastra Cagigas   +16 more
wiley   +1 more source

FINANCIAL LITERACY AMONG MALAY SOCIETY IN THE RIVERSIDE AREA OF CENTRAL KALIMANTAN

open access: yesAl-Banjari: Jurnal Ilmiah Ilmu-Ilmu Keislaman, 2019
Tujuan utama dari penelitian ini adalah untuk mengidentifikasi dan menganalisis tingkat kesadaran terhadap literasi keuangan di antara masyarakat Melayu di daerah tepi sungai melalui studi kasus di Desa Tanjung Putri, Kalimantan Tengah.
Alfina Rahmatia
doaj   +1 more source

The Early Sufi Tradition in Hamadān, Nahāwand, and Abhar

open access: yesAmerican Journal of Islam and Society, 2023
Research on the early Sufis of Hamadān, Nahāwand, and Abhar holds immense significance in comprehending the development of Sufism in the Jibāl region. This article provides an in-depth exploration of the initial stages of Sufism’s formation, focusing on
Fateh Saeidi
doaj   +1 more source

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