Results 51 to 60 of about 243,792 (206)
Basin Research, Volume 38, Issue 3, May–June 2026.New U–Pb zircon dating shows the Rewan Group was deposited between ~250 and 233 million years ago and that sedimentation shifted across the basin through time, with earlier deposition in the foredeep and later deposition in the back bulge. Testing multiple dating approaches and grain‐selection strategies improves confidence in these age estimates and ...
Matthew Scipione +6 more
wiley +1 more source
E3 Ubiquitin Ligases: Structures, Biological Functions, Diseases, and Therapy
MedComm, Volume 6, Issue 12, December 2025.E3 ligases function as critical regulators of cellular protein degradation, and their dysregulation is a core pathogenic mechanism in a wide array of human diseases, including cancer, cardiovascular conditions, neurodegenerative disorders, and autoimmune diseases.
Haochen Wang +6 more
wiley +1 more source
Journal of Neuroscience, 2020 Decline of protein quality control in neurons contributes to age-related neurodegenerative disorders caused by misfolded proteins. 4E-BP1 is a key node in the regulation of protein synthesis, as activated 4E-BP1 represses global protein translation ...
S. Dastidar +7 more
semanticscholar +1 more source
BEDIUZZAMAN SAID NURSI AND THE SUFI TRADITION
Al-Jami'ah: Journal of Islamic Studies, 2005 Berbicara tentang pribadi dan pemikiran Bediuzzaman Said Nursi, artikel ini dimaksudkan untuk mengungkap jati diri tokoh sufi modern dari Turki ini.
M. Machasin
doaj +1 more source
Journal of Biological Chemistry, 2020 Activation of the immune costimulatory molecule cluster of differentiation 40 (CD40) in Müller glia has been implicated in the initiation of diabetes-induced retinal inflammation.
Sadie K. Dierschke +4 more
semanticscholar +1 more source
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment
MedComm, Volume 6, Issue 8, August 2025.The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang +10 more
wiley +1 more source
MENGGAGAS REFORMASI PENDIDIKAN ISLAM: TELAAH FILOSOFIS PARADIGMATIK
Ulumuna, 2007 Discourse of religious education reform highlights at least two important pillars, philosophical and theoretical framework. Both frameworks are convinced as strong foundation of religious education development under rational-empirical principles of world
Ismail Thoib
doaj +1 more source
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Nature Communications, 2018 Aberrant expression of long noncoding RNA H19 has been associated with tumour progression, but the underlying molecular tumourigenesis mechanisms remain largely unknown.
Z. Wu +18 more
semanticscholar +1 more source
Translational Psychiatry, 2020 The 15q11.2 BP1-BP2 (Burnside-Butler) deletion is a rare copy number variant impacting four genes ( NIPA1, NIPA2, CYFIP1, and TUBGCP5 ), and carries increased risks for developmental delay, intellectual disability, and neuropsychiatric disorders ...
M. Farrell +15 more
semanticscholar +1 more source
Pendidikan Keluarga Dalam Al-Qur’an (Kajian Tafsir Tematik)
Madaniyah: Terciptanya Insan Akademis Berkualitas & Berakhlak Mulia, 2016 Ikatan perkawinan merupakan sarana pertama untuk membentuk keluarga. Baik dan buruknya keluarga ditentukan oleh bagaimana basis keluarga itu dibentuk. Keluarga juga bertanggung jawab atas keberlangsungan masing-masing anggotanya, baik tanggung jawab ...
Srifariyati .
doaj