Results 71 to 80 of about 12,167,877 (179)

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen, Huanle Qi, Yapeng Xue, Yaqi Zhang, Zhuo Zhang, Shun Xu, Shixin Liao, Xiaoyu Zeng, Jiayi Wu, Xinrui Lv, Qiankun He, Pingping Zhu   +11 more
wiley   +1 more source

Expression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma

, 2018
Feng Li,1,2,* Qingshui Wang,3,* Xiaoxue Xiong,3 Chenyi Wang,3 Xiaohua Liu,4 Ziqiang Liao,3 Ke Li,3 Bifeng Xie,5 Yao Lin3 1Department of Pathology, Provincial Clinical Medical College, Fujian Medical University, Fuzhou, Fujian Province, People’s ...
Liu X, Wang CY, Wang Q, Li F, Lin Y, Liao ZQ, Li K, Xiong X, Xie B   +8 more
core  

Strategi Implementasi Pengarusutamaan Gender Bidang Pendidikan Islam

Al-Tahrir, 2011
Islam encourages Moslems to seek for knowledge regardless the area boundary, age, and field of interest. However, the Islamic education in Indonesia has not been able to facilitate men and women to obtain equal education.
Mufidah Ch
doaj  

Supplementary Figure S2 from 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

, 2019
Supplementary Figure S2 shows A, the first intron of EIF4E-BP1 as an active target for epigenetic regulation of transcription; and B, 4NQO-induced tumors in eif4e-bp1/2 KO mice.
Victoria Wu (291871), Nahum Sonenberg (9676877), Nijiro Nohata (14938505), Zhiyong Wang (14937261), Xiaodong Feng (325840), Dana J. Steffen (14938511), Philip Tofilon (293813), Qianming Chen (325860), J. Silvio Gutkind (90145), Alfredo A. Molinolo (14938496), Daniel Martin (14938499), Panomwat Amornphimoltham (14889146), Amy Wahba (14924039), Xingyu Wu (4372774), Mara Gilardi (14938508), Michael Allevato (4255819), Joseph Califano (265988), Scott M. Lippman (11522115), Mizuo Ando (4663048), Lynn Vitale-Cross (14938502)   +19 more
core   +1 more source

Association between LRRK2 and 4E-BP1 protein levels in normal and malignant cells [PDF]

, 2012
Translational control is a crucial component of cancer development and progression. Eukaryotic initiation factor (eIF) 4E mediates eIF4F association with the mRNA 5' cap structure to stimulate cap-dependent translation initiation.
López, Laura, Armengol Rosell, Gemma, Coch, Laura, Pons López, Berta, Livingstone, Mark, Sonenberg, Nahum, Ramón y Cajal, Santiago   +6 more
core   +1 more source

Estudi de 4E-BP1 i la seva regulació en càncer de mama [PDF]

, 2011
Nombroses malalties presenten alteracions en el procés de traducció de proteïnes; això ha fet que en els darrers anys incrementi la recerca sobre els mecanismes que regulen l'expressió gènica dels organismes a nivell traduccional.
Armengol Rosell, Gemma, Pons López, Berta, Meseguer Navarro, Anna, Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular   +3 more
core   +1 more source

The Role of Cholesterol Metabolism and Its Regulation in Tumor Development

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Within the tumor microenvironment, tumor cells undergo metabolic reprogramming of cholesterol due to intrinsic cellular alterations and changes in the extracellular milieu. Furthermore, cholesterol reprogramming within this microenvironment influences the immune landscape of tumors, facilitating immune evasion and consequently ...
Yongmei Wu, Wenqian Song, Min Su, Jing He, Rong Hu, Youbo Zhao   +5 more
wiley   +1 more source

Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells

, 2008
BP1, a homeobox gene, is overexpressed in the bone marrow of 63% of acute myeloid leukemia patients. In this study, we compared the growth-inhibitory and cyto-differentiating activities of all-trans retinoic acid (ATRA) in NB4 (ATRA-responsive) and R4 ...
Stevenson, H, Awwad, RT, Campbell, CL, Berg, PE, Costello, M, Do, K, Fu, SW, LO COCO, FRANCESCO   +7 more
core   +1 more source

Kompetensi Guru Pendidikan Agama Islam Dalam Melaksanakan Kurikulum Tingkat Satuan Pendidikan

Kodifikasia, 2011
Keberagaman  kemampuan  guru  dalam  penguasaan  materi pembelajaran  atau  bahan  ajar  dan  penerapannya  dalam  proses belajar  mengajar  akan  berdampak  pada  munculnya  keragaman pencapaian  kompetensi  peserta  didik  pascapembelajaran.
Ju’ subaidi
doaj   +1 more source

Effect of LRRK2 on 4E-BP1 phosphorylation in mouse brain.

, 2013
Total 4E-BP1 immunoprecipitates or input lysates from the (A) cerebral cortex or (B) striatum of WT and LRRK2 KO mice, or human LRRK2 (R1441C or G2019S) transgenic (TG) and non-transgenic (NTG) mice were analyzed by Western blot analysis with antibodies ...
Adamantios Mamais (302600), Darren J. Moore (154952), Liliane Glauser (154950), Klodjan Stafa (154945), Philip J. Webber (185205), Elpida Tsika (302602), Andrew B. West (185211), Rina Bandopadhyay (302603), Alzbeta Trancikova (154943)   +8 more
core   +1 more source