Autoimmun betegségekben szerepet játszó új, diagnosztikus epitópok, valamint Fc receptorhoz kötődő és effektor funkciót kiváltó IgG Fc peptidkimérák azonosítása, szintézise és funkcionális jellemzése = Identification, synthesis and functional characterisation of new, diagnostic epitopes in autoimmune diseases, and of IgG Fc peptide chimeras binding to Fc receptor and triggering effector function [PDF]
, 2011 Autoimmun hólyagos bőrbetegségekre jellemző B- és T-sejt epitóppeptideket szintetizáltunk szilárdfázisú peptidszintézissel, Fmoc/tBu stratégiával. A peptideket tisztítottuk, azonosítottuk.
Bartos, Ádám +6 more
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Functions of p120ctn in development and disease [PDF]
, 2012 p120 catenin (p120ctn), a component of the cadherin-catenin complex, was the first member to be identified in a most interesting subfamily of the Armadillo family. Several p120ctn isoforms are generated by alternative splicing.
Pieters, Tim +2 more
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PLoS ONE, 2012 Bullous pemphigoid is an autoimmune blistering skin disease associated with autoantibodies against the dermal-epidermal junction. Passive transfer of antibodies against BP180/collagen (C) XVII, a major hemidesmosomal pemphigoid antigen, into neonatal ...
Eva Oswald +7 more
doaj +1 more source
Shedding of Collagen XVII/BP180 [PDF]
Journal of Biological Chemistry, 2004 Claus-Werner Franzke +4 more
openaire +1 more source
Diagnostic challenge: Juvenile bullous pemphigoid with a negative
Pediatric DermatologyAbstractBullous pemphigoid (BP) is an autoimmune blistering disease primarily affecting the elderly, whereas cases of juvenile BP are rare. Both types of BP are typically mediated by autoantibodies targeting the NC16A region of BP180; however, a small subset of adult patient sera react to other regions of the protein.
Janet A. Fairley +4 more
openaire +2 more sources
, 2010 International audienceUlcerative colitis, primary sclerosing cholangitis, and anti-glomerular basement membrane disease (anti-GBM) are three rare immune diseases with incompletely under-stood pathogenic mechanisms.
Bouguen, Guillaume +6 more
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The role of the innate immune response in HPV-related oral and oropharyngeal cancer [PDF]
, 2014 Introduction. During the last 20 years, the incidence of HPV-associated oropharyngeal cancer is increased. Principal actors of the innate immune response against HPV are represented by the TLRs (Toll like receptors).
Bufo, P. +5 more
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A rare case of keloid combined with bullous pemphigoid
Dermatology ReportsKeloids and bullous pemphigoid (BP) are two clinically and pathophysiologically distinct dermatologic disorders – the former involves abnormal scar formation due to excess collagen deposition, while the latter is an autoimmune blistering disease.
Ying Zhang +6 more
doaj +1 more source
Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid
Scientific Reports, 2017 Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis.
Pei Qiao +6 more
doaj +1 more source
Levantamento de reconhecimento de alta intensidade dos solos da folha Marapanim, Estado do Pará. [PDF]
, 2012 Caracterização da área. Localização. Vegetação. Geologia. Relevo. Hidrografia. Clima. Metodologia. Solos. Critérios e características diferenciais para caracterização e classificação dos solos. Descrição das classes de solos. Latossolo Amarelo. Podzólico
CAPECHE, C. L. +3 more
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