Results 71 to 80 of about 5,159 (241)

Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15 [PDF]

, 2016
Traceable truncated Neuropeptide Y (NPY) analogues with Y₁ receptor (Y₁R) affinity and selectivity are highly desirable tools in studying receptor location, regulation, and biological functions.
Herbert Herzog, Holliday N. D., Körner M., Lei Zhang, Matheus H. Tempone, Mengjie Liu, Michel M. C., Nicholas D. Holliday, Philip E. Thompson, Rachel R. Richardson, Simon J. Mountford, Thiele T. E.   +11 more
core   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Regrettable substitution? Comparative study of the effect profile of bisphenol A and eleven analogues in an in vitro test battery

Environmental Sciences Europe
Background Bisphenol A (BPA) is currently one of the most widely used synthetic chemicals in the production of a wide range of plastics. Due to its diverse endocrine disrupting potential alternative bisphenols, also referred to as analogues, have been ...
Natalie Reininger, Jörg Oehlmann
doaj   +1 more source

Analysis of the Detection of Organophosphate Pesticides in Aqueous Solutions Using Hydrogen-Bond Acidic Coating on SH-SAW Devices [PDF]

, 2012
The work presented in this paper focuses on the synthesis and characterization of a hybrid organic/inorganic chemically sensitive layer for rapid detection and analysis of OPs in aqueous solutions using SH-SAW devices.
Josse, Fabien, PhD, Mensah-Brown, Arnold Kweku, Mlambo, Darlington, Schneider, Susan C., PhD   +3 more
core   +1 more source

Large values of the Gowers-Host-Kra seminorms [PDF]

, 2011
The \emph{Gowers uniformity norms} $\|f\|_{U^k(G)}$ of a function $f: G \to \C$ on a finite additive group $G$, together with the slight variant $\|f\|_{U^k([N])}$ defined for functions on a discrete interval $[N] := \{1,...,N\}$, are of importance in ...
Eisner, Tanja, Tao, Terence
core   +2 more sources

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives

Toxicology, 2019
Recent studies report widespread usage or exposure to a variety of chemicals with structural or functional similarity to bisphenol A (BPA), referred to as BPA analogues or derivatives. These have been detected in foodstuffs, house dust, environmental samples, human urine or blood, and consumer products. Compared to BPA, relatively little is known about
Katherine, Pelch, Jessica A, Wignall, Alexandra E, Goldstone, Pam K, Ross, Robyn B, Blain, Andrew J, Shapiro, Stephanie D, Holmgren, Jui-Hua, Hsieh, Daniel, Svoboda, Scott S, Auerbach, Fredrick M, Parham, Scott A, Masten, Vickie, Walker, Andrew, Rooney, Kristina A, Thayer   +14 more
openaire   +2 more sources

Cashiers and bisphenols: Occupational exposure and health implications in south China

Emerging Contaminants
Bisphenols are ubiquitous chemicals used in various industries, raising concerns due to their potential to disrupt endocrine systems, particularly among occupational populations.
Zhenni Zhu, Yanan Pan, Xiang Chen, Xin Wei, Xiaoyue Zhou, Zixiong Tang, Renli Yin, Xiaoyang Jiao, Adela Jing Li   +8 more
doaj   +1 more source

Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway

Environment International, 2023
Despite being one of the most world's widely used and mass-produced compounds, bisphenol A (BPA) has a wide range of toxic effects. Bisphenol P (BPP), an alternative to BPA, has been detected in many foods.
Nana Ma, Diao Ma, Xia Liu, Lining Zhao, Lei Ma, Dan Ma, Sijun Dong   +6 more
doaj   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

Advanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang, Tingting Tong, Pengxi Shi, Xiaofan Chen, Chenhao Wang, Qingyuan Weng, Sihan Chen, Linli Que, Qi Chen, Yuehua Li, Qiang Zhu, Jiantao Li   +11 more
wiley   +1 more source