Results 51 to 60 of about 99,125 (300)

PCSK9 inhibitors patterns of use in France from nationwide repeated cross-sectional and cohort studies

Scientific Reports
PCSK9 inhibitors (PCSK9i) are indicated in combination with statins and/or ezetimibe to intensify LDL-cholesterol lowering and reduce the risks of atherosclerotic cardiovascular disease.
Allison Singier, Anne Bénard-Laribière, Ana Jarne-Munoz, Antoine Pariente, Gwenaelle Veyrac, Julien Bezin   +5 more
doaj   +1 more source

Resistensi Wereng Cokelat Terhadap Insektisida Yang Beredar Di Sentra Produksi Padi [PDF]

, 2016
Research on brown planthopper (BPH), (Nilaparvata lugens (Stal.) resistant to insecticide using dipping method was carried out in the wet season (WS) of 2011/2012 at Indonesian Center for Rice Research, Sukamandi.
E, B. S. (Baehaki), Iswanto, E. H. (E), Munawar, D. (D)   +2 more
core   +1 more source

Multi‐Level Confinement Single‐Molecule Charge Transfer Activated PRET for Near‐Infrared Targeted Cell Imaging

Advanced Science, EarlyView.
The cascade supramolecular assembly of charge‐transfer arrays not only triggered a topological transformation from nanofiber to nanorod and vesicles, but also promoted single‐molecule phosphorescent resonance energy transfer, expanding phosphorescence emission at 500 nm to near‐infrared delayed fluorescence emission at 650 nm with a lifetime of 11.20 ...
Zhuo Lei, Sai Li, Pei‐Ao Sun, Yong Chen, Xuejian Zhang, Yu Liu   +5 more
wiley   +1 more source

Relationship Between Serum Testosterone and Severity of Lower Urinary Tract Symptoms Among Malaysian Men

Société Internationale d’Urologie Journal, 2022
BackgroundLower urinary tract symptoms (LUTS) are commonly experienced among ageing males. The increasing prevalence of late-onset hypogonadism suggests a possible relationship between serum testosterone and severity of LUTS.
Suzliza Shukor , Fam Xeng Inn, Zulkifli Md Zainuddin   +2 more
doaj   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Long-Term Blood Pressure Variability and Risk of Age-Related Macular Degeneration in Older Adults: The ALIENOR Study

Ophthalmology Science
Purpose: Long-term blood pressure variability (BPV) has emerged as a risk factor for various health problems, including eye diseases, independent of blood pressure (BP) levels.
Blondy Kayembe-Mulumba, MD, MPH, Karen Leffondré, PhD, Bénédicte M.J. Merle, PhD, Jean-François Korobelnik, MD, PhD, Catherine Helmer, MD, PhD, Christophe Tzourio, MD, PhD, Cécile Delcourt, PhD, Audrey Cougnard-Grégoire, PhD, Marie-Noëlle Delyfer, MD, PhD   +8 more
doaj   +1 more source

Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis

Advanced Science, EarlyView.
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan, Yunping Chen, Wei Zhou, Yanghong Xu, Junran Huang, Yi Chen, Jizhou Meng, Guoxin Yao, Wenchao Huang   +8 more
wiley   +1 more source

Evaluating pedestrian crossing safety: Implementing and evaluating a convolutional neural network model trained on paired aerial and subjective perspective images

Heliyon
With pedestrian crossings implicated in a significant proportion of vehicle-pedestrian accidents and the French government's initiatives to improve pedestrian safety, there is a pressing need for efficient, large-scale evaluation of pedestrian crossings.
Dylan Russon, Antoine Guennec, Juan Naredo-Turrado, Binbin Xu, Cédric Boussuge, Valérie Battaglia, Benoit Hiron, Emmanuel Lagarde   +7 more
doaj   +1 more source

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

Chemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source