Results 151 to 160 of about 123,103 (378)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Evaluating the Efficiency of Milwaukee Brace on Scoliosis Deformity: A Systematic Review of Literature [PDF]

open access: yesIranian Rehabilitation Journal
Objectives: Scoliosis is a three-dimensional deformity of the spine that can be treated using various treatment approaches. The use of braces is one of the most commonly used treatment methods for controlling curve progression.
Mohammad Taghi Karimi   +2 more
doaj  

Seismic Behavior Of Steel Structure With Buckling- Restrained Braces

open access: green, 2015
Mahdi Karimi   +4 more
openalex   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Seismic Retrofit of an Existing Reinforced Concrete Building with Buckling-restrained Braces [PDF]

open access: diamond, 2021
Massimiliano Ferraioli   +3 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Effect of a Long-Term Corrective Exercises With Using Brace on Cobb Angle and Postural Control of a Girl With Adolescence Idiopathic Scoliosis

open access: yesPhysical Treatments, 2019
Purpose: Scoliosis is a three-dimensional deformity of the spine in which the resulting imbalance accompanied by the changes in muscle and nervous components can harm the postural control.
Mehdi Gheitasi   +2 more
doaj  

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