Results 141 to 150 of about 25,846 (308)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Skew braces of squarefree order
, 2020 Let n ≥ 1 be a squarefree integer, and let M, A be two groups of order n. Using our previous results on the enumeration of Hopf-Galois structures on Galois extensions of fields of squarefree degree, we determine the number of skew braces (up to ...
AA Alabdali (21870980) +1 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
On a family of simple skew braces
Several constructions have been given for families of simple braces, but few examples are known of simple skew braces which are not braces. In this paper, we exhibit the first example of an infinite family of simple skew braces which are not braces and ...
Byott, Nigel P.
core +1 more source
Physical Treatments, 2019 Purpose: Scoliosis is a three-dimensional deformity of the spine in which the resulting imbalance accompanied by the changes in muscle and nervous components can harm the postural control.
Mehdi Gheitasi +2 more
doaj
A Finite Element Analysis-Based Modeling and Evaluation Method for Sternum Support Brace
IEEE AccessSternum support braces are commonly used in thoracic surgery to secure the chest after open chest procedures. Despite their widespread use in postoperative recovery, current modeling and performance evaluation methods have significant limitations that ...
Linhua Lv +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source