New insights into swine dysentery: faecal shedding, macro and microscopic lesions and biomarkers in early and acute stages of Brachyspira hyodysenteriae infection. [PDF]
Porcine Health Manag[EN] Background: Swine dysentery (SD) is a severe mucohaemorrhagic colitis in pigs caused classically by Brachyspira hyodysenteriae. Although several aspects of B.
Pérez-Pérez L +6 more
europepmc +3 more sources
Fecal shedding of Brachyspira spp. on a farrow-to-finish swine farm with a clinical history of "Brachyspira hampsonii"-associated colitis. [PDF]
BMC Vet Res, 2013 Abstract Background Brachyspira associated diarrhea is a re-emerging concern for Canadian swine producers. To identify critical control points for reducing the impact of Brachyspira on production, improved diagnostic tools and a better understanding of the on-farm epidemiology of these pathogens are ...
Patterson AH +5 more
europepmc +4 more sources
An optimized swine dysentery murine model to characterize shedding and clinical disease associated with "Brachyspira hampsonii" infection. [PDF]
BMC Vet Res, 2017 The development of a mouse model as an in vivo pathogenicity screening tool for Brachyspira spp. has advanced the study of these economically important pathogens in recent years. However, none of the murine models published to date have been used to characterize the clinical signs of disease in mice, instead focusing on pathology following oral ...
Ek CE +8 more
europepmc +3 more sources
Molecular Epidemiology of Novel Pathogen "Brachyspira hampsonii" Reveals Relationships between Diverse Genetic Groups, Regions, Host Species, and Other Pathogenic and Commensal Brachyspira Species. [PDF]
J Clin Microbiol, 2015 ABSTRACT Outbreaks of bloody diarrhea in swine herds in the late 2000s signaled the reemergence of an economically significant disease, swine dysentery, in the United States. Investigations confirmed the emergence of a novel spirochete in swine, provisionally designated “ Brachyspira hampsonii ,” with two ...
Mirajkar NS +3 more
europepmc +4 more sources
Characterization and Recognition of Brachyspira hampsonii sp. nov., a Novel Intestinal Spirochete That Is Pathogenic to Pigs. [PDF]
J Clin Microbiol, 2016 ABSTRACT Swine dysentery (SD) is a mucohemorrhagic colitis of swine classically caused by infection with the intestinal spirochete Brachyspira hyodysenteriae . Since around 2007, cases of SD have occurred in North America associated with a different strongly beta-hemolytic spirochete that has been ...
Mirajkar NS +4 more
europepmc +4 more sources
Xenotransplantation, Volume 30, Issue 5, September/October 2023., 2023 Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal +14 more
wiley +1 more source
In vitro attenuation of a virulent swine isolate of Brachyspira hampsonii [PDF]
Pathogens and Disease, 2017 Brachyspira hampsonii causes dysentery-like disease in infected pigs. Serial passage of a virulent swine isolate (P13) one-hundred times in laboratory culture medium was conducted to produce an attenuated strain, and to identify genomic determinants of virulence through comparison of genome sequences of the original and passaged strains.
Jason Byron D S, Perez +5 more
openaire +2 more sources
Cross-reactions in specific Brachyspira spp. PCR assays caused by “Brachyspira hampsonii” isolates [PDF]
Journal of Veterinary Diagnostic Investigation, 2016 An emerging novel spirochete in swine, provisionally designated “ Brachyspira hampsonii,” has been detected worldwide. It has been associated with swine dysentery and cannot be differentiated from B. hyodysenteriae, the classical etiologic agent of this disease, using standard phenotypic methods. We evaluated cross-reactions of “ B.
Luis M, Aller-Morán +3 more
openaire +2 more sources
Phenotypic and molecular characterization of a novel strongly hemolytic Brachyspira species, provisionally designated “Brachyspira hampsonii” [PDF]
Journal of Veterinary Diagnostic Investigation, 2012 Since 2007, outbreaks of severe bloody diarrhea and hemorrhagic colitis have been reported in the United States and Canada. Though the primary causative agent of swine dysentery is Brachyspira hyodysenteriae, which is strongly hemolytic, the current report describes the isolation of a novel strongly hemolytic Brachyspira sp. This novel Brachyspira sp.
Yogesh, Chander +3 more
openaire +2 more sources
Fluorescent in situ hybridization for detection of “Brachyspira hampsonii” in porcine colonic tissues [PDF]
Journal of Veterinary Diagnostic Investigation, 2013 Swine dysentery is classically associated with infection by the strongly beta-hemolytic Brachyspira hyodysenteriae; however, the proposed novel species “ Brachyspira hampsonii” has also been isolated from clinical cases of dysentery in the United States and Canada. Microbial culture is highly sensitive for detecting Brachyspira in clinical samples but
Eric R, Burrough +4 more
openaire +2 more sources