In vitro attenuation of a virulent swine isolate of Brachyspira hampsonii [PDF]
Pathogens and Disease, 2017 Brachyspira hampsonii causes dysentery-like disease in infected pigs. Serial passage of a virulent swine isolate (P13) one-hundred times in laboratory culture medium was conducted to produce an attenuated strain, and to identify genomic determinants of virulence through comparison of genome sequences of the original and passaged strains.
Jason Byron D S, Perez +5 more
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Phenotypic and molecular characterization of a novel strongly hemolytic Brachyspira species, provisionally designated “ Brachyspira hampsonii ” [PDF]
Journal of Veterinary Diagnostic Investigation, 2012 Since 2007, outbreaks of severe bloody diarrhea and hemorrhagic colitis have been reported in the United States and Canada. Though the primary causative agent of swine dysentery is Brachyspira hyodysenteriae, which is strongly hemolytic, the current report describes the isolation of a novel strongly hemolytic Brachyspira sp.
Yogesh, Chander +3 more
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Fluorescent in situ hybridization for detection of “ Brachyspira hampsonii ” in porcine colonic tissues [PDF]
Journal of Veterinary Diagnostic Investigation, 2013 Swine dysentery is classically associated with infection by the strongly beta-hemolytic Brachyspira hyodysenteriae; however, the proposed novel species “ Brachyspira hampsonii” has also been isolated from clinical cases of dysentery in the United States and Canada.
Eric R, Burrough +4 more
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Cross-reactions in specific Brachyspira spp. PCR assays caused by “ Brachyspira hampsonii ” isolates [PDF]
Journal of Veterinary Diagnostic Investigation, 2016 An emerging novel spirochete in swine, provisionally designated “ Brachyspira hampsonii,” has been detected worldwide. It has been associated with swine dysentery and cannot be differentiated from B. hyodysenteriae, the classical etiologic agent of this disease, using standard phenotypic methods. We evaluated cross-reactions of “ B. hampsonii” isolates
Luis M, Aller-Morán +3 more
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Comparison of culture, polymerase chain reaction, and fluorescent in situ hybridization for detection of Brachyspira hyodysenteriae and “ Brachyspira hampsonii ” in pig feces [PDF]
Journal of Veterinary Diagnostic Investigation, 2014 Swine dysentery is characterized by mucohemorrhagic diarrhea and can occur following infection by Brachyspira hyodysenteriae or “ Brachyspira hampsonii ”. A definitive diagnosis is often based on the isolation of strongly beta-hemolytic spirochetes from selective culture or by the application of species-specific polymerase chain reaction (PCR) assays ...
Bailey L, Wilberts +4 more
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PLoS ONE, 2014 Diet has been implicated as a major factor impacting clinical disease expression of swine dysentery and Brachyspira hyodysenteriae colonization. However, the impact of diet on novel pathogenic strongly beta-hemolytic Brachyspira spp.
Bailey L Wilberts +8 more
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2022 TlyA proteins are expressed in a variety of pathogenic bacteria and possess dual hemolytic and ribosomal RNA methyltransferase functions. While the mechanism of TlyA mediated rRNA methylation is well understood, relatively little is known about the mechanism of TlyA induced hemolysis.TlyA protein from the pig pathogen Brachyspira hampsonii was ...
Brandon A, Keith +2 more
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Microbial Pathogenesis, 2020 Swine dysentery (SD) is a global, production-limiting disease of pigs in commercial farms. It is associated with infection by Brachyspira hyodysenteriae and B. hampsonii, and characterized by mucohaemorrhagic diarrhea and colitis, SD prevention, treatment or control relies heavily on antimicrobials as no commercial vaccines are available.
Matheus O, Costa, John C S, Harding
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for rapid identification of Brachyspira species isolated from swine, including the newly described “ Brachyspira hampsonii ” [PDF]
Journal of Veterinary Diagnostic Investigation, 2014 The Brachyspira species traditionally associated with swine dysentery and other diarrheal diseases in pigs are Brachyspira hyodysenteriae, Brachyspira pilosicoli, and, to a lesser extent, Brachyspira murdochii. “ Brachyspira hampsonii” is a recently proposed novel species that causes clinical disease similar to that caused by B. hyodysenteriae.
Hallie L, Warneke +4 more
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PLoS ONE, 2018 Swine dysentery (SD) is an economically important diarrheal disease in pigs caused by different strongly hemolytic Brachyspira (B.) species, such as B. hyodysenteriae, B. suanatina and B. hampsonii.
Jessica Joerling +5 more
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